State Key Laboratory of Digital Medical Engineering, School of Biomedical Engineering, Hainan University, Haikou 570100, China.
Key Laboratory of Biomedical Engineering of Hainan Province, One Health Institute, Hainan University, Haikou 570100, China.
Biosensors (Basel). 2024 Feb 19;14(2):111. doi: 10.3390/bios14020111.
This article presents the design of a low-power, low-noise neural signal amplifier for neural recording. The structure reduces the current consumption of the amplifier through current scaling technology and lowers the input-referred noise of the amplifier by combining a source degeneration resistor and current reuse technologies. The amplifier was fabricated using a 0.18 μm CMOS MS RF G process. The results show the front-end amplifier exhibits a measured mid-band gain of 40 dB/46 dB and a bandwidth ranging from 0.54 Hz to 6.1 kHz; the amplifier's input-referred noise was measured to be 3.1 μVrms, consuming a current of 3.8 μA at a supply voltage of 1.8 V, with a Noise Efficiency Factor (NEF) of 2.97. The single amplifier's active silicon area is 0.082 mm.
本文提出了一种用于神经记录的低功耗、低噪声神经信号放大器的设计。该结构通过电流缩放技术降低了放大器的电流消耗，并通过源退化电阻和电流复用技术降低了放大器的输入参考噪声。该放大器采用 0.18μm CMOS MS RF G 工艺制造。结果表明，前端放大器的测量中频带增益为 40dB/46dB，带宽范围为 0.54Hz 至 6.1kHz；放大器的输入参考噪声为 3.1μVrms，在 1.8V 电源电压下消耗电流为 3.8μA，噪声效率因子（NEF）为 2.97。单个放大器的有源硅面积为 0.082mm。
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