Uchida T, Imoto M, Watanabe Y, Miura K, Dobashi T, Matsuda N, Sawa T, Naganawa H, Hamada M, Takeuchi T
J Antibiot (Tokyo). 1985 Sep;38(9):1171-81. doi: 10.7164/antibiotics.38.1171.
From the culture broth of Streptomyces nodosus MH190-16F3, four new antibiotics have been isolated, and named saquayamycins A, B, C and D. The compounds are glycosides of aquayamycin, and among aquayamycin-group antibiotics they are most closely related to P-1894B (vineomycin A1). All saquayamycins act on Gram-positive bacteria and inhibit the growth of adriamycin-sensitive and adriamycin-resistant P388 leukemia cells.
从诺卡氏链霉菌MH190 - 16F3的培养液中分离出了四种新抗生素，分别命名为沙夸霉素A、B、C和D。这些化合物是阿夸霉素的糖苷，在阿夸霉素类抗生素中，它们与P - 1894B（酒霉素A1）关系最为密切。所有沙夸霉素都作用于革兰氏阳性菌，并抑制对阿霉素敏感和耐药的P388白血病细胞的生长。
