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用于预测儿科重症监护病房危急事件的深度学习模型的开发。

Development of a deep learning model for predicting critical events in a pediatric intensive care unit.

作者信息

Lee In Kyung, Lee Bongjin, Park June Dong

机构信息

Department of Pediatrics, Seoul St. Mary's Hospital, Seoul, Korea.

Department of Pediatrics, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.

出版信息

Acute Crit Care. 2024 Feb;39(1):186-191. doi: 10.4266/acc.2023.01424. Epub 2024 Feb 20.

Abstract

BACKGROUND

Identifying critically ill patients at risk of cardiac arrest is important because it offers the opportunity for early intervention and increased survival. The aim of this study was to develop a deep learning model to predict critical events, such as cardiopulmonary resuscitation or mortality.

METHODS

This retrospective observational study was conducted at a tertiary university hospital. All patients younger than 18 years who were admitted to the pediatric intensive care unit from January 2010 to May 2023 were included. The main outcome was prediction performance of the deep learning model at forecasting critical events. Long short-term memory was used as a deep learning algorithm. The five-fold cross validation method was employed for model learning and testing.

RESULTS

Among the vital sign measurements collected during the study period, 11,660 measurements were used to develop the model after preprocessing; 1,060 of these data points were measurements that corresponded to critical events. The prediction performance of the model was the area under the receiver operating characteristic curve (95% confidence interval) of 0.988 (0.9751.000), and the area under the precision-recall curve was 0.862 (0.700-1.000).

CONCLUSIONS

The performance of the developed model at predicting critical events was excellent. However, follow-up research is needed for external validation.

摘要

背景

识别有心脏骤停风险的重症患者很重要,因为这为早期干预和提高生存率提供了机会。本研究的目的是开发一种深度学习模型,以预测心肺复苏或死亡等关键事件。

方法

这项回顾性观察研究在一家三级大学医院进行。纳入了2010年1月至2023年5月入住儿科重症监护病房的所有18岁以下患者。主要结果是深度学习模型预测关键事件的性能。长短期记忆被用作深度学习算法。采用五折交叉验证方法进行模型学习和测试。

结果

在研究期间收集的生命体征测量数据中,经过预处理后,11660个测量数据用于开发模型;其中1060个数据点对应于关键事件。该模型的预测性能为受试者工作特征曲线下面积(95%置信区间)为0.988(0.975 - 1.000),精确召回率曲线下面积为0.862(0.700 - 1.000)。

结论

所开发模型在预测关键事件方面的性能优异。然而,需要进行后续研究以进行外部验证。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/16f8/11002614/e4eb091b5e42/acc-2023-01424f1.jpg

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