Harbottle Zoe, Nötzel Amanda, Golding Michael A, Bhamra Manvir, Kopsch Isac, Wilking Erik, Jonsson Marina, Abrams Elissa M, Halbrich Michelle A, Simons Elinor, Roos Leslie E, Keddy-Grant Jill A, Gerstner Thomas V, St-Vincent Jo-Anne, Ekström Sandra, Protudjer Jennifer L P
Department of Pediatrics and Child Health, Rady Faculty of Health Sciences, Max Rady College of Medicine, University of Manitoba, Winnipeg, MB, Canada.
Children's Hospital Research Institute of Manitoba, 501G-715 McDermot Avenue, Winnipeg, MB, Canada.
Allergy Asthma Clin Immunol. 2024 Mar 22;20(1):21. doi: 10.1186/s13223-024-00883-x.
While the impacts of atopic dermatitis (AD) on maternal and child sleep outcomes have been previously explored, less is known about the associations between infantile AD and sleep quality and quantity.
To describe the perceived causes of AD-associated maternal sleep disturbances and the association between AD severity and infant sleep outcomes.
Mothers with infants aged < 19 months old with a diagnosis of AD were recruited from social media and medical clinics in Winnipeg, Canada between October 2021 and May 2022. Infant AD severity was classified using maternal-reported data on the Patient-Oriented Scoring Atopic Dermatitis tool (PO-SCORAD). Quantitative data were collected via a series of questionnaires with a subset of mothers subsequently completing semi-structured interviews. Quantitative and qualitative data were integrated in the discussion.
Mothers of infants with moderate/severe AD (6/12) were more likely to report their infant suffering from a higher degree of sleeplessness (i.e., ≥ 5 on a scale of 0-10) over the past 48 h compared to mothers of infants with mild AD (0/18). This was supported by qualitative findings where mothers described how their infant's sleep quality and quantity worsened with AD severity. Additionally, 7/32 mothers reported that their child's AD, regardless of severity, disturbed their sleep. Maternal sleep loss was most commonly attributed to infant itching (6/7), followed by worry (4/7).
Infantile AD severity was associated with worse sleep outcomes for both mothers and infants. We propose that maternal and infantile sleep quality and quantity can be improved by reducing AD severity through adherence to topical treatments.
虽然先前已经探讨了特应性皮炎（AD）对母婴睡眠结果的影响，但关于婴儿AD与睡眠质量和数量之间的关联知之甚少。
描述AD相关的母亲睡眠障碍的感知原因以及AD严重程度与婴儿睡眠结果之间的关联。
2021年10月至2022年5月期间，从加拿大温尼伯的社交媒体和医疗诊所招募了患有AD的19个月以下婴儿的母亲。婴儿AD严重程度使用患者导向的特应性皮炎评分工具（PO-SCORAD）中母亲报告的数据进行分类。通过一系列问卷收集定量数据，随后一部分母亲完成半结构化访谈。定量和定性数据在讨论中进行整合。
与轻度AD婴儿的母亲（0/18）相比，中度/重度AD婴儿的母亲（6/12）更有可能报告其婴儿在过去48小时内遭受更高程度的失眠（即0-10分制中≥5分）。定性研究结果支持了这一点，母亲们描述了随着AD严重程度的增加，婴儿的睡眠质量和数量如何恶化。此外，7/32的母亲报告说，无论严重程度如何，孩子的AD都会干扰她们的睡眠。母亲睡眠不足最常见的原因是婴儿瘙痒（6/7），其次是担忧（4/7）。
婴儿AD严重程度与母亲和婴儿的睡眠结果较差有关。我们建议通过坚持局部治疗降低AD严重程度来改善母婴的睡眠质量和数量。
