Callen D F, Dale B M, Sage R E, Ford J H
Cancer Genet Cytogenet. 1985 Mar 1;16(1):45-8. doi: 10.1016/0165-4608(85)90076-7.
The breakpoints of a complex three-way translocation involving chromosomes X, #15, and #17 were resolved in a case of acute promyelocytic leukemia (APL). It is now apparent that similar cases of variant chromosome translocations are found in both chronic granulocytic leukemia (CGL) and APL. The morphological and clinical findings in this case emphasize the variability found in some cases of APL.
在一例急性早幼粒细胞白血病(APL)中,涉及X染色体、15号染色体和17号染色体的复杂三向易位断点得以解析。现在很明显,在慢性粒细胞白血病(CGL)和APL中都发现了类似的变异染色体易位病例。该病例的形态学和临床发现强调了部分APL病例中存在的变异性。