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人工肾脏:挑战与机遇。

Artificial kidney: Challenges and opportunities.

作者信息

Karageorgos Filippos F, Neiros Stavros, Karakasi Konstantina-Eleni, Vasileiadou Stella, Katsanos Georgios, Antoniadis Nikolaos, Tsoulfas Georgios

机构信息

Department of Transplantation Surgery, Center for Research and Innovation in Solid Organ Transplantation, Aristotle University School of Medicine, Thessaloniki 54642, Greece.

出版信息

World J Transplant. 2024 Mar 18;14(1):89025. doi: 10.5500/wjt.v14.i1.89025.

DOI:10.5500/wjt.v14.i1.89025
PMID:38576754
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10989479/
Abstract

This review aims to present the developments occurring in the field of artificial organs and particularly focuses on the presentation of developments in artificial kidneys. The challenges for biomedical engineering involved in overcoming the potential difficulties are showcased, as well as the importance of interdisciplinary collaboration in this marriage of medicine and technology. In this review, modern artificial kidneys and the research efforts trying to provide and promise artificial kidneys are presented. But what are the problems faced by each technology and to what extent is the effort enough to date?

摘要

本综述旨在介绍人工器官领域的发展情况,尤其着重于人工肾脏方面的进展。文中展示了生物医学工程在克服潜在困难时所面临的挑战,以及跨学科合作在医学与技术融合中的重要性。本综述还介绍了现代人工肾脏以及为研发人工肾脏所做的研究工作。但每种技术面临哪些问题,到目前为止这些努力的成效如何?

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2
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本文引用的文献

1
Kidney Bioengineering for Transplantation.肾脏生物工程移植。
Transplantation. 2023 Sep 1;107(9):1883-1894. doi: 10.1097/TP.0000000000004526. Epub 2023 Aug 21.
2
Wearable and implantable artificial kidney devices for end-stage kidney disease treatment: Current status and review.用于终末期肾病治疗的可穿戴式和植入式人工肾装置:现状与综述。
Artif Organs. 2023 Apr;47(4):649-666. doi: 10.1111/aor.14396. Epub 2022 Sep 21.
3
Wearable artificial kidney: problems, progress and prospects.可穿戴人工肾:问题、进展与前景
Nat Rev Nephrol. 2020 Oct;16(10):558-559. doi: 10.1038/s41581-020-0318-1.
4
Bioengineering strategies for nephrologists: kidney was not built in a day.生物工程策略助力肾病学家:肾脏不是一日建成的。
Expert Opin Biol Ther. 2020 May;20(5):467-480. doi: 10.1080/14712598.2020.1709439. Epub 2020 Jan 23.
5
A wearable artificial kidney for patients with end-stage renal disease.一种用于终末期肾病患者的可穿戴人工肾。
JCI Insight. 2016 Jun 2;1(8). doi: 10.1172/jci.insight.86397.
6
Creating a wearable artificial kidney: where are we now?打造可穿戴人工肾脏:我们目前进展如何?
Expert Rev Med Devices. 2015 Jul;12(4):373-6. doi: 10.1586/17434440.2015.1053466.
7
Timing of dialysis initiation: when to start? Which treatment?透析开始的时机:何时开始?采用哪种治疗方式?
J Ren Nutr. 2015 Mar;25(2):238-41. doi: 10.1053/j.jrn.2014.10.015. Epub 2014 Dec 31.
8
Biotechnological challenges of bioartificial kidney engineering.生物人工肾工程的生物技术挑战。
Biotechnol Adv. 2014 Nov 15;32(7):1317-1327. doi: 10.1016/j.biotechadv.2014.08.001. Epub 2014 Aug 16.
9
The bioartificial kidney.生物人工肾。
Transl Res. 2014 Apr;163(4):342-51. doi: 10.1016/j.trsl.2013.10.006. Epub 2013 Nov 5.
10
The bioartificial kidney: current status and future promise.生物人工肾:现状与未来前景。
Pediatr Nephrol. 2014 Mar;29(3):343-51. doi: 10.1007/s00467-013-2467-y. Epub 2013 Apr 26.