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甲氯芬那酸钠与缓冲阿司匹林及安慰剂治疗术后牙痛的比较。

Comparison of meclofenamate sodium with buffered aspirin and placebo in the treatment of postsurgical dental pain.

作者信息

Markowitz N R, Young S K, Rohrer M D, Turner J L

出版信息

J Oral Maxillofac Surg. 1985 Jul;43(7):517-22. doi: 10.1016/s0278-2391(85)80030-6.

DOI:10.1016/s0278-2391(85)80030-6
PMID:3859595
Abstract

The efficacy of meclofenamate sodium (Meclomen) at two different doses was compared with that of buffered aspirin and placebo in the control of postsurgical pain in a double-blind, randomized study of 205 patients. Meclofenamate sodium, 200 mg, was significantly better than meclofenamate sodium, 100 mg, in some efficacy parameters. Both doses of meclofenamate sodium were superior to buffered aspirin in most parameters of efficacy, and more effective than placebo in every parameter.

摘要

在一项针对205名患者的双盲随机研究中,比较了两种不同剂量的甲氯芬那酸钠(甲氯灭酸)与缓冲阿司匹林和安慰剂在控制术后疼痛方面的疗效。在某些疗效参数方面,200毫克的甲氯芬那酸钠明显优于100毫克的甲氯芬那酸钠。在大多数疗效参数上,两种剂量的甲氯芬那酸钠均优于缓冲阿司匹林,且在每个参数上都比安慰剂更有效。

相似文献

1
Comparison of meclofenamate sodium with buffered aspirin and placebo in the treatment of postsurgical dental pain.甲氯芬那酸钠与缓冲阿司匹林及安慰剂治疗术后牙痛的比较。
J Oral Maxillofac Surg. 1985 Jul;43(7):517-22. doi: 10.1016/s0278-2391(85)80030-6.
2
Comparison of meclofenamate sodium with buffered aspirin and placebo for the relief of postoperative dental pain.甲氯芬那酸钠与缓冲阿司匹林及安慰剂缓解术后牙痛的比较。
Clin Ther. 1987;9(6):594-601.
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Double-blind comparison of meclofenamate sodium plus codeine, meclofenamate sodium, codeine, and placebo for relief of pain following surgical removal of third molars.双盲比较甲氯芬那酸钠加可待因、甲氯芬那酸钠、可待因及安慰剂对拔除第三磨牙后疼痛的缓解作用。
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Double-blind comparison of meclofenamate sodium with codeine and placebo for the pain of episiotomy.甲氯芬那酸钠与可待因及安慰剂治疗会阴切开术后疼痛的双盲比较。
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Sodium meclofenamate ('Meclomen') in the treatment of rheumatoid arthritis: a double-blind comparison with aspirin and placebo.甲氯芬那酸钠(“美克洛明”)治疗类风湿性关节炎:与阿司匹林和安慰剂的双盲对照研究
Pharmatherapeutica. 1981;2(9):587-96.

引用本文的文献

1
Single dose oral aspirin for acute postoperative pain in adults.单剂量口服阿司匹林用于成人术后急性疼痛
Cochrane Database Syst Rev. 2012 Apr 18;2012(4):CD002067. doi: 10.1002/14651858.CD002067.pub2.
2
The efficacy of nonopioid analgesics for postoperative dental pain: a meta-analysis.非阿片类镇痛药用于术后牙痛的疗效:一项荟萃分析。
Anesth Prog. 1997 Fall;44(4):119-26.
3
Summary of the scientific literature for pain and anxiety control in dentistry. Journal literature, January-December, 1985.牙科疼痛与焦虑控制的科学文献综述。期刊文献,1985年1月至12月。
Anesth Prog. 1986 Sep-Oct;33(5):268-77.