Markowitz N R, Young S K, Rohrer M D, Turner J L
J Oral Maxillofac Surg. 1985 Jul;43(7):517-22. doi: 10.1016/s0278-2391(85)80030-6.
The efficacy of meclofenamate sodium (Meclomen) at two different doses was compared with that of buffered aspirin and placebo in the control of postsurgical pain in a double-blind, randomized study of 205 patients. Meclofenamate sodium, 200 mg, was significantly better than meclofenamate sodium, 100 mg, in some efficacy parameters. Both doses of meclofenamate sodium were superior to buffered aspirin in most parameters of efficacy, and more effective than placebo in every parameter.
在一项针对205名患者的双盲随机研究中,比较了两种不同剂量的甲氯芬那酸钠(甲氯灭酸)与缓冲阿司匹林和安慰剂在控制术后疼痛方面的疗效。在某些疗效参数方面,200毫克的甲氯芬那酸钠明显优于100毫克的甲氯芬那酸钠。在大多数疗效参数上,两种剂量的甲氯芬那酸钠均优于缓冲阿司匹林,且在每个参数上都比安慰剂更有效。