Guery B, Alfandari S, Leroy O, Georges H, D'escrivan T, Kipnis E, Mouton Y, Yazdanpanah Y
Réanimation médicale et maladies infectieuses, CH de Tourcoing, 135, rue Président-Coty, 59208 Tourcoing, France.
Service régional de maladies infectieuses et tropicales, CH de Tourcoing, 135, rue Président-Coty, 59208 Tourcoing, France.
Med Mal Infect. 2003 Jun;33(6):281-286. doi: 10.1016/S0399-077X(03)00200-2. Epub 2003 Jun 6.
In the Fall of 2002 a report from Guangdong Province in China showed the occurrence of an outbreak of atypical pneumonia. This outbreak rapidly progressed from China to Hong Kong, Singapore, Toronto, and the USA, to more than 25 countries worldwide and almost 3500 cases to date in april 2003. The clinical features associate a fever with mild respiratory symptoms which can progress to a typical acute respiratory distress syndrome requiring intensive care unit admission. Enteric forms with diarrhea were recently described in Hong Kong. The medical community responded very rapidly and united in front of this major health crisis. In a couple weeks, the agent, a new was isolated, therapeutic guidelines were proposed and measures to limit the outbreak diffusion were started worldwide. We summarize here the history of the outbreak, the clinical, laboratory and radiological features of SARS. April 2003 therapeutic guidelines are also reported.
2002年秋,中国广东省的一份报告显示出现了非典型肺炎疫情。此次疫情迅速从中国蔓延至香港、新加坡、多伦多和美国,进而扩散到全球25多个国家,截至2003年4月已有近3500例病例。其临床特征为发热伴轻度呼吸道症状,可进展为典型的急性呼吸窘迫综合征,需要入住重症监护病房。香港近期报告了伴有腹泻的肠道型病例。医学界对这一重大健康危机反应迅速且团结一致。在几周内,病原体——一种新型病毒被分离出来,提出了治疗指南,并在全球范围内启动了限制疫情扩散的措施。在此,我们总结此次疫情的历程、严重急性呼吸综合征(SARS)的临床、实验室及影像学特征。还报告了2003年4月的治疗指南。