1Department of Psychology, Yunnan Normal University, Kunming, Yunnan Province, P.R. China.
2Center for Cognition and Brain Disorders, School of Clinical Medicine and the Affiliated Hospital of Hangzhou Normal University, Hangzhou, P.R. China.
J Behav Addict. 2024 Apr 17;13(2):596-609. doi: 10.1556/2006.2024.00011. Print 2024 Jun 26.
Although internet gaming disorder (IGD) has been included in the DSM-5 for approximately 10 years, debate remains regarding its existence and classification.
The current research incorporated three approaches. First, implicit association tests were used to examine for potential dissociation between wanting and liking in IGD. Second, brain features in wanting and liking circuits were tested and compared with tobacco use disorder (TUD) when performing a cue-craving task to explore the neural features of wanting and liking. Third, dopaminergic systems were investigated in IGD and TUD using neuromelanin-sensitive MRI.
The implicit association test results supported a wanting-liking dissociation in IGD participants. Functional MRI data suggested neural correlates underlying wanting-liking dissociation in IGD and TUD participants, with positive correlations suggesting greater dissociation with increasing addiction severity. Neuromelanin results suggest dopaminergic differences in IGD and TUD relative to healthy control participants.
A wanting-liking dissociation in IGD participants suggests gaming motivations in IGD relating to incentive sensitization rather than hedonic responses. The neuromelanin-sensitive MRI results suggest dopaminergic involvement in IGD and TUD. The findings suggest similar brain-behaviour mechanisms for IGD and TUD based on an incentive-sensitization model for addiction, having implications for potential therapeutic strategies and policy-based interventions.
尽管互联网游戏障碍 (IGD) 已被纳入 DSM-5 约 10 年，但关于其存在和分类仍存在争议。
本研究采用了三种方法。首先，通过内隐联想测验来检验 IGD 中想要和喜欢之间是否存在潜在的分离。其次，在进行线索渴求任务时，测试并比较想要和喜欢回路中的大脑特征，以探索想要和喜欢的神经特征，同时将其与烟草使用障碍 (TUD) 进行比较。第三，使用神经黑色素敏感 MRI 研究 IGD 和 TUD 中的多巴胺能系统。
内隐联想测验的结果支持 IGD 参与者中存在想要-喜欢的分离。功能磁共振成像数据表明，IGD 和 TUD 参与者的想要-喜欢分离存在神经相关性，随着成瘾严重程度的增加，正相关提示分离程度更大。神经黑色素结果表明，与健康对照组相比，IGD 和 TUD 中的多巴胺能存在差异。
IGD 参与者中存在想要-喜欢的分离，表明 IGD 中的游戏动机与激励敏感化有关，而不是与享乐反应有关。神经黑色素敏感 MRI 的结果表明，IGD 和 TUD 中存在多巴胺能参与。这些发现基于成瘾的激励敏感化模型，表明 IGD 和 TUD 具有相似的大脑-行为机制，这对潜在的治疗策略和基于政策的干预措施具有重要意义。
