Mousavi Nazanin, Molaei Aghil, Alesaeidi Samira, Eftekhari Seas Nader, Effatpanah Mohammad
School of Psychology, Imam Khomeini University, Qazvin, Iran.
Faculty of Health, Student Research Committee, Mazandaran University of Medical Sciences, Sari, Iran.
Clin Pract Epidemiol Ment Health. 2024 Jan 29;20:e17450179276345. doi: 10.2174/0117450179276345240117043037. eCollection 2024.
Wegener's disease is an autoimmune condition affecting the respiratory tract and kidneys. Mental health assessment is crucial due to the impact of psychological disorders on the immune system. Despite this, there is limited community-based research on psychiatric disorders and personality traits among patients with Wegener's disease.
This study aimed to investigate the prevalence of psychiatric disorders and examine the predictive role of personality traits among patients with Wegener's disease.
A total of 100 patients met the inclusion and exclusion criteria, and all of them were selected to participate in the study. Out of them, 75 individuals completed the questionnaires. The instruments included the SCL-90 questionnaire and the NEO Big Five personality traits. The data were analysed using Stata software, and the prevalence of psychiatric disorders in different patient groups was determined using the chi-square method. The predictive role of personality traits in mental disorders was examined using multivariate regression.
The results revealed that paranoia (53.3%) and depression (44%) had the highest prevalence in terms of psychiatric disorders, while psychosis (17.3%) and hostility (25.33%) had the lowest prevalence. Additionally, the findings demonstrated a positive correlation between most psychiatric disorders and the neuroticism personality trait.
Given the influence of mental disorders on the immune system in Wegener's disease, it is essential to provide psychological care for these patients.
韦格纳肉芽肿病是一种影响呼吸道和肾脏的自身免疫性疾病。由于心理障碍对免疫系统有影响，心理健康评估至关重要。尽管如此，关于韦格纳肉芽肿病患者的精神障碍和人格特质，基于社区的研究仍然有限。
本研究旨在调查韦格纳肉芽肿病患者精神障碍的患病率，并检验人格特质的预测作用。
共有100名患者符合纳入和排除标准，全部被选入研究。其中75人完成了问卷调查。所用工具包括90项症状自评量表（SCL-90）问卷和大五人格量表（NEO）。使用Stata软件对数据进行分析，采用卡方检验确定不同患者组中精神障碍的患病率。使用多元回归检验人格特质在精神障碍中的预测作用。
结果显示，在精神障碍方面，偏执（53.3%）和抑郁（44%）的患病率最高，而精神病（17.3%）和敌对（25.33%）的患病率最低。此外，研究结果表明，大多数精神障碍与神经质人格特质之间存在正相关。
鉴于精神障碍对韦格纳肉芽肿病患者免疫系统的影响，为这些患者提供心理护理至关重要。
