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职业性噪声暴露、噪声性听力损失与高血压流行病学

Occupational noise exposure, noise-induced hearing loss, and the epidemiology of high blood pressure.

作者信息

Talbott E, Helmkamp J, Matthews K, Kuller L, Cottington E, Redmond G

出版信息

Am J Epidemiol. 1985 Apr;121(4):501-14. doi: 10.1093/oxfordjournals.aje.a114028.

Abstract

The role of noise exposure in the etiology of high blood pressure is unclear. A cross-sectional study of occupational noise exposure and high blood pressure was conducted in March 1981-August 1982 in a group of blue-collar workers from a noisy (greater than or equal to 89 dBA) and a less noisy plant (less than 81 dBA). There were 197 randomly sampled men from the noisier plant and 169 from the comparison factory. Clinical examinations, audiograms and a psychologic inventory were conducted. Body mass index, alcohol intake, and family history of hypertension were comparable for the two groups. There was no difference in mean systolic or diastolic blood pressure between workers in the two plants. There was, however, a strong relationship between severe noise-induced hearing loss (greater than or equal to 65 dBA loss at 3, 4, or 6 k Hz) and high blood pressure (greater than or equal to 90 mmHg diastolic or taking blood pressure medication) in the 56+ age group in both plants after adjusting for risk factors (p less than 0.02). Multiple regression analysis revealed that in the noisier plant, body mass index, severe noise-induced hearing loss, and noisy hobbies explained a significant amount of the variation in diastolic pressure (p less than 0.05) R2 = 0.19. This suggests that there may be a population at increased risk for hearing loss and high blood pressure.

摘要

噪声暴露在高血压病因中的作用尚不清楚。1981年3月至1982年8月,对来自一个噪声较大(大于或等于89分贝)工厂和一个噪声较小(小于81分贝)工厂的一组蓝领工人进行了职业噪声暴露与高血压的横断面研究。从噪声较大的工厂随机抽取了197名男性,从对照工厂抽取了169名男性。进行了临床检查、听力图检查和心理量表测试。两组的体重指数、酒精摄入量和高血压家族史具有可比性。两个工厂工人的平均收缩压或舒张压没有差异。然而,在调整风险因素后,两个工厂56岁及以上年龄组中,严重噪声性听力损失(在3、4或6千赫兹时损失大于或等于65分贝)与高血压(舒张压大于或等于90毫米汞柱或正在服用降压药物)之间存在密切关系(p小于0.02)。多元回归分析显示,在噪声较大的工厂中,体重指数、严重噪声性听力损失和嘈杂的爱好解释了舒张压变化的很大一部分(p小于0.05),R2 = 0.19。这表明可能存在听力损失和高血压风险增加的人群。

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