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绿色合成银纳米粒子;一种具有多种应用的可持续方法。

Green Synthesis of Silver Nanoparticles; A Sustainable Approach with Diverse Applications.

机构信息

Department of Pharmaceutics, Mahatma Gandhi Institute of Pharmacy, Lucknow, Uttar Pradesh, India.

Department of Pharmacology, Mahatma Gandhi Institute of Pharmacy, Lucknow, Uttar Pradesh, India.

出版信息

Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2023 Dec 21;39:e20230007. doi: 10.62958/j.cjap.2023.007.

Abstract

Silver nanoparticles (AgNPs) have garnered significant attention in recent years due to their unique properties and diverse applications across various industries. This review provides an overview of the synthesis methods, characterization techniques, applications, regulatory guidelines, and challenges associated with AgNPs. Green synthesis routes, utilizing natural extracts or biomolecules, have emerged as environmentally sustainable alternatives for producing AgNPs with reduced environmental impact. Characterization techniques such as spectroscopy, microscopy, and chromatography are employed to analyze the physicochemical properties of AgNPs and ensure their quality and stability. AgNPs find applications in biomedical, environmental, and consumer product sectors, including wound dressings, water purification filters, cosmetics, and medical devices, owing to their antimicrobial, catalytic, and optical properties. Regulatory guidelines play a crucial role in ensuring the safe and responsible use of AgNPs, addressing concerns related to biocompatibility, toxicity, and environmental impact. However, challenges remain in standardization, scalability, and long-term safety assessment of AgNP-based products. Future research efforts should focus on optimizing synthesis methods, enhancing characterization techniques, and addressing regulatory gaps to unlock the full potential of AgNPs while ensuring their safety and sustainability. Overall, AgNPs offer promising opportunities for addressing global challenges and driving technological innovation across diverse sectors.

摘要

近年来,由于其独特的性质和在各个行业中的广泛应用,银纳米粒子(AgNPs)引起了人们的极大关注。本文综述了 AgNPs 的合成方法、表征技术、应用、监管指南以及相关挑战。利用天然提取物或生物分子的绿色合成途径已成为生产具有降低环境影响的 AgNPs 的环境可持续替代方法。光谱学、显微镜和色谱学等表征技术用于分析 AgNPs 的物理化学性质,以确保其质量和稳定性。AgNPs 因其具有抗菌、催化和光学性质,在生物医学、环境和消费产品领域得到了广泛应用,包括伤口敷料、水净化过滤器、化妆品和医疗器械。监管指南在确保 AgNPs 的安全和负责任使用方面发挥着至关重要的作用,解决了与生物相容性、毒性和环境影响相关的问题。然而,在 AgNP 基产品的标准化、可扩展性和长期安全性评估方面仍存在挑战。未来的研究工作应侧重于优化合成方法、增强表征技术,并解决监管空白,以在确保安全和可持续性的同时充分发挥 AgNPs 的潜力。总的来说,AgNPs 为应对全球挑战和推动各领域技术创新提供了有前景的机会。

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