Chernyshov Pavel V, Sampogna Francesca, Raimondi Giulia, Zouboulis Christos C, Boffa Michael J, Marron Servando E, Manolache Liana, Pustišek Nives, Bettoli Vincenzo, Koumaki Dimitra, Bewley Anthony P, Dreno Brigitte, Tomas-Aragones Lucia
Department of Dermatology and Venereology, National Medical University, Kiev, Ukraine.
Clinical Epidemiology Unit, Istituto Dermopatico dell'Immacolata IDI-IRCCS, Rome, Italy.
JAAD Int. 2024 Mar 25;16:9-17. doi: 10.1016/j.jdin.2024.03.007. eCollection 2024 Sep.
Participating members of the European Academy of Dermatology and Venereology Task Forces on quality of life (QoL) and Patient Oriented Outcomes and Acne, Rosacea and Hidradenitis Suppurativa initiated data collection in 9 European countries and formed the list of the most relevant topics for acne patients.
The aim of this study was to develop a new acne-specific health-related QoL instrument based on the list of the most relevant topics for acne patients.
After assessment by acne patients ( = 715) on how clear and relevant the items in the prototype questionnaire were, a group of experts on acne and QoL performed discussions on items inclusion, which resulted in a series of 21 items. Then another group of acne patients ( = 1502) filled in the new version of the instrument. A factor analysis was conducted on the 21-item version.
Three-factor model with 19 items indicated a satisfactory fit. The three dimensions were called: Socioemotional; Symptoms; Stigma and Suicidal thoughts.
Included patients and experts may not fully represent acne patients and health care professionals worldwide.
A final 19-item version of the Quality of Life Relevance-Acne was developed.
欧洲皮肤病与性病学会生活质量（QoL）、以患者为导向的结果以及痤疮、酒渣鼻和化脓性汗腺炎特别工作组的参与成员于2006年在9个欧洲国家开展了数据收集工作，并确定了痤疮患者最相关的主题清单。
本研究旨在基于痤疮患者最相关的主题清单，开发一种新的特定于痤疮的健康相关生活质量工具。
在痤疮患者（n = 715）对原型问卷中的条目清晰程度和相关性进行评估之后，一组痤疮和生活质量专家就条目纳入进行了讨论，最终形成了一系列21个条目的问卷。随后另一组痤疮患者（n = 1502）填写了该工具的新版本。对21个条目的版本进行了因子分析。
19个条目的三因素模型显示拟合良好。这三个维度分别称为：社会情感；症状；耻辱感和自杀念头。
纳入的患者和专家可能无法完全代表全球的痤疮患者和医疗保健专业人员。
最终形成了一份19个条目的生活质量相关性-痤疮问卷。
