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出院后一年内，新冠病毒感染（COVID-19）与非新冠病毒感染重症监护病房患者在生活质量、家庭支持、肺活量测定及6分钟步行距离方面的差异

Quality of Life, Family Support, Spirometry, and 6-Minute Walking Distance Differences between COVID-19 and Non-COVID-19 Intensive Care Unit Patients in One Year Following Hospital Discharge.

作者信息

Avgeri Konstantina, Mantzarlis Konstantinos, Gerovasileiou Effrosyni, Deskata Konstantina, Chatzi Maria, Fotakopoulos George, Sgantzos Markos, Tsolaki Vasiliki, Zakynthinos Epaminondas, Makris Demosthenes

机构信息

Medical Deparment, University of Thessaly, 41336 Larissa, Greece.

出版信息

Healthcare (Basel). 2024 May 13;12(10):996. doi: 10.3390/healthcare12100996.

DOI:10.3390/healthcare12100996
PMID:38786407
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11121675/
Abstract

BACKGROUND

Critically ill patients after Intensive Care Unit (ICU) discharge may present disability in their cognitive and physical functions.

OBJECTIVES

To investigate the quality of life (QoL) of both COVID-19 and non-COVID-19 patients following ICU discharge, lung function, and physical performance of participants.

METHODS

This study was prospective and conducted between 2020 and 2021 in the "X" hospital. If patients were Mechanically-Ventilated (MV) > 48 h, they were included.

RESULTS

Fifty COVID-19 and seventy-two non-COVID-19 participants were included in this study. The mean (SD) of the total SF-36 scores at COVID-19 patients at hospital discharge and 3 and 12 months were 46.5 (14.5), 68.6 (17.8), and 82.3 (8.9) ( < 0.05), while non-COVID-19 participants were 48.5 (12.1), 72.2 (9.9), and 82.7 (5.4) ( < 0.05). The forced expiratory volume in one second (FEV1) and 6-minute walking distance (6MWD) were assessed at 3 and 12 months and significantly improved over 12 months.

CONCLUSION

The QoL of COVID-19 patients improved significantly over time as FEV1 and 6MWD.

摘要

背景

重症监护病房（ICU）出院后的重症患者可能存在认知和身体功能障碍。

目的

调查ICU出院后的新型冠状病毒肺炎（COVID-19）患者和非COVID-19患者的生活质量（QoL）、肺功能及参与者的身体表现。

方法

本研究为前瞻性研究，于2020年至2021年在“X”医院进行。纳入机械通气（MV）超过48小时的患者。

结果

本研究纳入了50名COVID-19患者和72名非COVID-19参与者。COVID-19患者出院时、出院后3个月和12个月的SF-36总分均值（标准差）分别为46.5（14.5）、68.6（17.8）和82.3（8.9）（<0.05），而非COVID-19参与者分别为48.5（12.1）、72.2（9.9）和82.7（5.4）（<0.05）。在3个月和12个月时评估了一秒用力呼气量（FEV1）和6分钟步行距离（6MWD），且在12个月内显著改善。

结论

随着FEV1和6MWD的改善，COVID-19患者的生活质量随时间显著提高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f2a/11121675/5149e077a22d/healthcare-12-00996-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f2a/11121675/6716f9c1c920/healthcare-12-00996-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f2a/11121675/eedd4205abd6/healthcare-12-00996-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f2a/11121675/30dca58fa6a7/healthcare-12-00996-g003a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f2a/11121675/5149e077a22d/healthcare-12-00996-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f2a/11121675/6716f9c1c920/healthcare-12-00996-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f2a/11121675/eedd4205abd6/healthcare-12-00996-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f2a/11121675/30dca58fa6a7/healthcare-12-00996-g003a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f2a/11121675/5149e077a22d/healthcare-12-00996-g004.jpg

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