Rosellen Jens, Dittmar Florian, Hauptmann Arne, Diemer Thorsten, Schuppe Hans-Christian, Schagdarsurengin Undraga, Fritzenwanker Moritz, Wagenlehner Florian, Pilatz Adrian
Clinic of Urology, Pediatric Urology and Andrology, Justus Liebig University Giessen, Rudolf-Buchheim-Strasse 7, 35392 Giessen, Germany.
Institute for Medical Microbiology, Justus Liebig University Giessen, 35390 Giessen, Germany.
J Clin Med. 2024 May 14;13(10):2884. doi: 10.3390/jcm13102884.
Chronic prostatitis/chronic pelvic pain syndrome CP/CPPS is a rather common condition and in recent years many studies have shown contradictory results regarding its impact on semen quality. This prospective cohort study set out to investigate how CP/CPPS affected the parameters of semen in a prospective cohort of patients compared with the WHO 2021 reference group. From 2013 to 2022, a total of 1071 patients with suspicion of CP/CPPS received a comprehensive andrological examination. Complete semen analysis was carried out in compliance with WHO 2010 guidelines, comparing every study population semen variable to the WHO 2021 reference group (n~3500). All evaluated semen parameters had median values that fell within a normal range. Nonetheless, approximately 25% of patients had values for each semen variable that were lower than the WHO reference group's fifth percentile. In particular, bacteriospermia was associated with a negative impact on semen volume. This is the largest study that compares all standard semen parameters in patients suffering from CP/CPPS to WHO 2021 reference values. It provides evidence of an impairment of conventional semen parameters.
慢性前列腺炎/慢性盆腔疼痛综合征（CP/CPPS）是一种相当常见的病症，近年来，许多研究就其对精液质量的影响得出了相互矛盾的结果。这项前瞻性队列研究旨在调查与世界卫生组织（WHO）2021年参考组相比，CP/CPPS如何影响一组前瞻性患者队列的精液参数。2013年至2022年期间，共有1071名疑似CP/CPPS的患者接受了全面的男科检查。按照WHO 2010指南进行了完整的精液分析，将每个研究人群的精液变量与WHO 2021年参考组（n≈3500）进行比较。所有评估的精液参数中位数均落在正常范围内。尽管如此，约25%的患者每个精液变量的值低于WHO参考组的第五百分位数。特别是，精液细菌污染对精液量有负面影响。这是将CP/CPPS患者的所有标准精液参数与WHO 2021年参考值进行比较的最大规模研究。它提供了传统精液参数受损的证据。
