Arruda Gabriel L, Raymundo Maria Teresa F R, Cruz-Santos Mónica M, Shibukawa Vinícius P, Jofre Fanny M, Prado Carina A, da Silva Silvio S, Mussatto Solange I, Santos Júlio C
Department of Biotechnology, Engineering School of Lorena, University of São Paulo, Lorena, Brazil.
Department of Biotechnology and Biomedicine, Technical University of Denmark, Kongens Lyngby, Denmark.
Crit Rev Biotechnol. 2025 Mar;45(2):393-412. doi: 10.1080/07388551.2024.2349581. Epub 2024 May 30.
Second generation biorefineries play an important role in the production of renewable energy and fuels, utilizing forest and agro-industrial residues and by-products as raw materials. The integration of novel bioproducts, such as: xylitol, β-carotene, xylooligosaccharides, and biopigments into the biorefinery's portfolio can offer economic benefits in the valorization of lignocellulosic materials, particularly cellulosic and hemicellulosic fractions. Fungal biopigments, known for their additional antioxidant and antimicrobial properties, are appealing to consumers and can have applications in various industrial sectors, including food and pharmaceuticals. The use of lignocellulosic materials as carbon and nutrient sources for the growth medium helps to reduce production costs, increasing the competitiveness of fungal biopigments in the market. In addition, the implementation of biopigment production in biorefineries allows the utilization of underutilized fractions, such as hemicellulose, for value-added bioproducts. This study deals with the potential of fungal biopigments production in second generation biorefineries in order to diversify the produced biomolecules together with energy generation. A comprehensive and critical review of the recent literature on this topic has been conducted, covering the major possible raw materials, general aspects of second generation biorefineries, the fungal biopigments and their potential for incorporation into biorefineries.
第二代生物精炼厂在可再生能源和燃料生产中发挥着重要作用，它利用森林和农工业残渣及副产品作为原材料。将新型生物产品，如木糖醇、β-胡萝卜素、低聚木糖和生物色素纳入生物精炼厂的产品组合，可为木质纤维素材料（特别是纤维素和半纤维素部分）的增值带来经济效益。真菌生物色素以其额外的抗氧化和抗菌特性而闻名，对消费者具有吸引力，并可应用于包括食品和制药在内的各个工业领域。使用木质纤维素材料作为生长培养基的碳源和营养源有助于降低生产成本，提高真菌生物色素在市场上的竞争力。此外，在生物精炼厂中生产生物色素能够利用未充分利用的部分，如半纤维素，来生产高附加值的生物产品。本研究探讨了在第二代生物精炼厂中生产真菌生物色素的潜力，以便在生产生物分子的同时实现能源多样化。本文对该主题的近期文献进行了全面而批判性的综述，涵盖了主要的可能原材料、第二代生物精炼厂的一般方面、真菌生物色素及其纳入生物精炼厂的潜力。
