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复杂热图可视化。

Complex heatmap visualization.

作者信息

Gu Zuguang

机构信息

Molecular Precision Oncology Program, National Center for Tumor Diseases (NCT) Heidelberg Germany.

出版信息

Imeta. 2022 Aug 1;1(3):e43. doi: 10.1002/imt2.43. eCollection 2022 Sep.


DOI:10.1002/imt2.43
PMID:38868715
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10989952/
Abstract

Heatmap is a widely used statistical visualization method on matrix-like data to reveal similar patterns shared by subsets of rows and columns. In the R programming language, there are many packages that make heatmaps. Among them, the package provides the richest toolset for constructing highly customizable heatmaps. can easily establish connections between multisource information by automatically concatenating and adjusting a list of heatmaps as well as complex annotations, which makes it widely applied in data analysis in many fields, especially in bioinformatics, to find hidden structures in the data. In this article, we give a comprehensive introduction to the current state of , including its modular design, its rich functionalities, and its broad applications.

摘要

热图是一种广泛应用于矩阵类数据的统计可视化方法,用于揭示行和列子集共享的相似模式。在R编程语言中,有许多用于制作热图的包。其中,该包为构建高度可定制的热图提供了最丰富的工具集。它可以通过自动连接和调整热图列表以及复杂注释,轻松地在多源信息之间建立联系,这使得它在许多领域的数据分析中得到广泛应用,尤其是在生物信息学中,用于发现数据中的隐藏结构。在本文中,我们对该包的当前状态进行了全面介绍,包括其模块化设计、丰富的功能以及广泛的应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d80/10989952/090a2a97de02/IMT2-1-e43-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d80/10989952/edaf91ed6950/IMT2-1-e43-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d80/10989952/6a6d5ae0d358/IMT2-1-e43-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d80/10989952/5755cf634354/IMT2-1-e43-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d80/10989952/f46fe7a822c0/IMT2-1-e43-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d80/10989952/cc35f3e0bbb2/IMT2-1-e43-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d80/10989952/090a2a97de02/IMT2-1-e43-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d80/10989952/edaf91ed6950/IMT2-1-e43-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d80/10989952/6a6d5ae0d358/IMT2-1-e43-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d80/10989952/5755cf634354/IMT2-1-e43-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d80/10989952/f46fe7a822c0/IMT2-1-e43-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d80/10989952/cc35f3e0bbb2/IMT2-1-e43-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d80/10989952/090a2a97de02/IMT2-1-e43-g007.jpg

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本文引用的文献

[1]
simplifyEnrichment: A Bioconductor Package for Clustering and Visualizing Functional Enrichment Results.

Genomics Proteomics Bioinformatics. 2023-2

[2]
Make Interactive Complex Heatmaps in R.

Bioinformatics. 2022-2-7

[3]
spiralize: an R package for visualizing data on spirals.

Bioinformatics. 2022-2-7

[4]
Proteogenomic and metabolomic characterization of human glioblastoma.

Cancer Cell. 2021-4-12

[5]
Glioblastoma epigenome profiling identifies SOX10 as a master regulator of molecular tumour subtype.

Nat Commun. 2020-12-18

[6]
cola: an R/Bioconductor package for consensus partitioning through a general framework.

Nucleic Acids Res. 2021-2-22

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Longitudinal analyses reveal immunological misfiring in severe COVID-19.

Nature. 2020-7-27

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Immunogenomic Landscape of Hematological Malignancies.

Cancer Cell. 2020-9-14

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Cell Syst. 2020-5-20

[10]
Galaxy HiCExplorer 3: a web server for reproducible Hi-C, capture Hi-C and single-cell Hi-C data analysis, quality control and visualization.

Nucleic Acids Res. 2020-7-2

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