4种筛查方法的验证、分析灵敏度、成本效益及比较
Verification, Analytical Sensitivity, Cost-effectiveness, and Comparison of 4 Screening Methods.
作者信息
Komorowski Adam S, Aftanas Patryk, Porter Vanessa, Katz Kevin, Kozak Robert A, Li Xena X
机构信息
Medical Microbiology, Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
Department of Health Research Methodology, Evidence, and Impact, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.
出版信息
Open Forum Infect Dis. 2024 Jan 10;11(6):ofae017. doi: 10.1093/ofid/ofae017. eCollection 2024 Jun.
Abstract
In this verification study, we compare and contrast the performance characteristics of chromogenic agar culture, direct polymerase chain reaction (PCR), and broth enrichment followed by culture or PCR for the detection of colonization. We find that culture and PCR both offer excellent performance, with broth enrichment offering little performance advantage given its cost.
摘要
在这项验证研究中，我们比较并对比了用于检测定植的显色琼脂培养、直接聚合酶链反应（PCR）以及肉汤增菌后再进行培养或PCR的性能特征。我们发现培养和PCR均具有出色的性能，鉴于肉汤增菌的成本，其性能优势不大。
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