David E. Vance is a Professor, School of Nursing, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Pariya L. Fazeli is an Associate Professor, School of Nursing, University of Alabama at Birmingham, Birmingham, Alabama, USA.
J Assoc Nurses AIDS Care. 2024;35(2):104-121. doi: 10.1097/JNC.0000000000000449. Epub 2024 Jan 18.
Speed of processing (SOP) cognitive training may improve indicators of the quality of life (QoL) in people living with HIV. In this 2-year, longitudinal, randomized, controlled trial, 216 participants ages 40 years and older with HIV-associated neurocognitive disorder or borderline HIV-associated neurocognitive disorder were assigned to one of three groups: (a) 10 hr of SOP training (n = 70); (b) 20 hr of SOP training (n = 73), or (c) 10 hr of internet navigation control training (a contact control group; n = 73). Participants completed several QoL measures at baseline, posttest, and Year 1 and Year 2 follow-ups. Using linear mixed-effect models, no strong pattern of training effects across QoL outcomes was apparent, with small-magnitude, nonsignificant, between-group differences in depression, locus of control, and Medical Outcomes Study-HIV scales. In conclusion, despite prior work showing some transfer of SOP cognitive training improving QoL, that was not observed. Implications for research and practice are posited.
速度处理（SOP）认知训练可以改善艾滋病毒感染者的生活质量（QoL）指标。在这项为期 2 年的纵向、随机、对照试验中，216 名年龄在 40 岁及以上、患有与艾滋病毒相关的认知障碍或边缘性与艾滋病毒相关的认知障碍的参与者被分配到以下三个组之一：（a）10 小时的 SOP 训练（n = 70）；（b）20 小时的 SOP 训练（n = 73），或（c）10 小时的互联网导航控制训练（接触对照组；n = 73）。参与者在基线、后测和第 1 年和第 2 年随访时完成了几项 QoL 测量。使用线性混合效应模型，没有明显的训练效果模式，抑郁、控制源和医疗结果研究-艾滋病毒量表的组间差异较小且无统计学意义。总之，尽管之前的工作表明 SOP 认知训练在改善 QoL 方面有一定的转移效果，但并没有观察到。对研究和实践的影响进行了推测。
