噬菌体T4 dam与宿主大肠杆菌dam DNA-腺嘌呤甲基转移酶基因的共同进化起源。
Common evolutionary origin of the phage T4 dam and host Escherichia coli dam DNA-adenine methyltransferase genes.
作者信息
Hattman S, Wilkinson J, Swinton D, Schlagman S, Macdonald P M, Mosig G
出版信息
J Bacteriol. 1985 Nov;164(2):932-7. doi: 10.1128/jb.164.2.932-937.1985.
Abstract
We compared the known DNA nucleotide and encoded amino acid sequences of the Escherichia coli and bacteriophage T4 dam (DNA-adenine methyltransferase) genes. Despite the absence of any DNA sequence homology, there were four regions (11 to 33 residues long) of amino acid sequence homology containing 45 to 64% identity. These results suggest that the genes for these two enzymes have a common evolutionary origin.
摘要
我们比较了大肠杆菌和噬菌体T4的dam（DNA腺嘌呤甲基转移酶）基因的已知DNA核苷酸序列和编码的氨基酸序列。尽管不存在任何DNA序列同源性，但存在四个氨基酸序列同源区域（长度为11至33个残基），其同一性为45%至64%。这些结果表明，这两种酶的基因有共同的进化起源。
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