Barathi Selvaraj, Ramalingam Srinivasan, Krishnasamy Gopinath, Lee Jintae
School of Chemical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea.
Department of Horticulture & Life Science, Yeungnam University, Gyeongsan 38541, Republic of Korea.
Pharmaceutics. 2024 Jul 11;16(7):923. doi: 10.3390/pharmaceutics16070923.
As contemporary technology advances, scientists are striving to identify new approaches to managing several diseases. Compared to the more popular physiochemical synthesis, the plant-derived combination of metallic nanoparticles using plant secondary metabolites as a precursor has a number of benefits, including low expenses, low energy consumption, biocompatibility, and medicinal usefulness. This study intends to explore the impacts of using plant-derived synthetic materials including metallic nanoparticles (NPs), emphasizing the benefits of their broad use in next-generation treatments for cancer, diabetes, Alzheimer's, and vector diseases. This comprehensive analysis investigates the potential of plant-derived remedies for diseases and looks at cutting-edge nanoformulation techniques aimed at addressing the function of the nanoparticles that accompany these organic substances. The purpose of the current review is to determine how plant extracts contribute to the synthesis of Silver nanoparticles (AgNPs), Gold nanoparticles (GtNPs), and platinum nanoparticles (PtNPs). It provides an overview of the many phytocompounds and their functions in biomedicine, including antibacterial, antioxidant, anticancer, and anti-inflammatory properties. Furthermore, this study placed a special focus on a range of applications, including drug delivery systems, diagnostics and therapy, the present benefits of nanoparticles (NPs), their biomedical uses in medical technology, and their toxicities.
随着当代技术的进步，科学家们正在努力寻找治疗多种疾病的新方法。与更流行的物理化学合成方法相比，以植物次生代谢物为前体的植物源金属纳米颗粒组合具有许多优点，包括成本低、能耗低、生物相容性和药用价值。本研究旨在探讨使用包括金属纳米颗粒（NPs）在内的植物源合成材料的影响，强调其在癌症、糖尿病、阿尔茨海默病和媒介疾病的下一代治疗中广泛应用的益处。这项全面的分析研究了植物源药物治疗疾病的潜力，并审视了旨在解决与这些有机物质相关的纳米颗粒功能的前沿纳米制剂技术。当前综述的目的是确定植物提取物如何促进银纳米颗粒（AgNPs）、金纳米颗粒（GtNPs）和铂纳米颗粒（PtNPs）的合成。它概述了多种植物化合物及其在生物医学中的功能，包括抗菌、抗氧化、抗癌和抗炎特性。此外，本研究特别关注了一系列应用，包括药物递送系统、诊断和治疗、纳米颗粒（NPs）的当前益处、它们在医疗技术中的生物医学用途以及它们的毒性。
