Choi Joon Yul, Yoo Tae Keun
Department of Biomedical Engineering, Yonsei University, Wonju, South Korea.
Department of Ophthalmology, Hangil Eye Hospital, 35 Bupyeong-Daero, Bupyeong-Gu, Incheon, 21388, South Korea.
Med Biol Eng Comput. 2025 Jan;63(1):75-87. doi: 10.1007/s11517-024-03182-0. Epub 2024 Aug 12.
We developed a scoring system for assessing glaucoma risk using demographic and laboratory factors by employing a no-code approach (automated coding) using ChatGPT-4. Comprehensive health checkup data were collected from the Korea National Health and Nutrition Examination Survey. Using ChatGPT-4, logistic regression was conducted to predict glaucoma without coding or manual numerical processes, and the scoring system was developed based on the odds ratios (ORs). ChatGPT-4 also facilitated the no-code creation of an easy-to-use risk calculator for glaucoma. The ORs for the high-risk groups were calculated to measure performance. ChatGPT-4 automatically developed a scoring system based on demographic and laboratory factors, and successfully implemented a risk calculator tool. The predictive ability of the scoring system was comparable to that of traditional machine learning approaches. For high-risk groups with 1-2, 3-4, and 5 + points, the calculated ORs for glaucoma were 1.87, 2.72, and 15.36 in the validation set, respectively, compared with the group with 0 or fewer points. This study presented a novel no-code approach for developing a glaucoma risk assessment tool using ChatGPT-4, highlighting its potential for democratizing advanced predictive analytics, making them readily available for clinical use in glaucoma detection.
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