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Development of a novel scoring system for glaucoma risk based on demographic and laboratory factors using ChatGPT-4.

作者信息

Choi Joon Yul, Yoo Tae Keun

机构信息

Department of Biomedical Engineering, Yonsei University, Wonju, South Korea.

Department of Ophthalmology, Hangil Eye Hospital, 35 Bupyeong-Daero, Bupyeong-Gu, Incheon, 21388, South Korea.

出版信息

Med Biol Eng Comput. 2025 Jan;63(1):75-87. doi: 10.1007/s11517-024-03182-0. Epub 2024 Aug 12.


DOI:10.1007/s11517-024-03182-0
PMID:39129037
Abstract

We developed a scoring system for assessing glaucoma risk using demographic and laboratory factors by employing a no-code approach (automated coding) using ChatGPT-4. Comprehensive health checkup data were collected from the Korea National Health and Nutrition Examination Survey. Using ChatGPT-4, logistic regression was conducted to predict glaucoma without coding or manual numerical processes, and the scoring system was developed based on the odds ratios (ORs). ChatGPT-4 also facilitated the no-code creation of an easy-to-use risk calculator for glaucoma. The ORs for the high-risk groups were calculated to measure performance. ChatGPT-4 automatically developed a scoring system based on demographic and laboratory factors, and successfully implemented a risk calculator tool. The predictive ability of the scoring system was comparable to that of traditional machine learning approaches. For high-risk groups with 1-2, 3-4, and 5 + points, the calculated ORs for glaucoma were 1.87, 2.72, and 15.36 in the validation set, respectively, compared with the group with 0 or fewer points. This study presented a novel no-code approach for developing a glaucoma risk assessment tool using ChatGPT-4, highlighting its potential for democratizing advanced predictive analytics, making them readily available for clinical use in glaucoma detection.

摘要

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引用本文的文献

[1]
Application prospect of large language model represented by ChatGPT in ophthalmology.

Int J Ophthalmol. 2025-9-18

[2]
Large language models in the management of chronic ocular diseases: a scoping review.

Front Cell Dev Biol. 2025-6-18

[3]
Automated detection of retinal artery occlusion in fundus photography via self-supervised deep learning and multimodal interpretability using a multimodal AI chatbot.

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[4]
Retinal vein occlusion risk prediction without fundus examination using a no-code machine learning tool for tabular data: a nationwide cross-sectional study from South Korea.

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[5]
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[6]
Assessment of Large Language Models in Cataract Care Information Provision: A Quantitative Comparison.

Ophthalmol Ther. 2025-1

本文引用的文献

[1]
Integrating Deep Learning with Electronic Health Records for Early Glaucoma Detection: A Multi-Dimensional Machine Learning Approach.

Bioengineering (Basel). 2024-6-7

[2]
Deep-Learning Based Automated Segmentation and Quantitative Volumetric Analysis of Orbital Muscle and Fat for Diagnosis of Thyroid Eye Disease.

Invest Ophthalmol Vis Sci. 2024-5-1

[3]
Intelligent diagnosis of the severity of disease conditions in COVID-19 patients based on the LASSO method.

Front Public Health. 2024

[4]
Code-Free Machine Learning Approach for EVO-ICL Vault Prediction: A Retrospective Two-Center Study.

Transl Vis Sci Technol. 2024-4-2

[5]
Evaluating ChatGPT-4.0's data analytic proficiency in epidemiological studies: A comparative analysis with SAS, SPSS, and R.

J Glob Health. 2024-3-29

[6]
Utility of artificial intelligence-based large language models in ophthalmic care.

Ophthalmic Physiol Opt. 2024-5

[7]
Deep learning prediction of steep and flat corneal curvature using fundus photography in post-COVID telemedicine era.

Med Biol Eng Comput. 2024-2

[8]
The Use of ChatGPT to Assist in Diagnosing Glaucoma Based on Clinical Case Reports.

Ophthalmol Ther. 2023-12

[9]
Alabama Screening and Intervention for Glaucoma and Eye Health through Telemedicine (AL-SIGHT): Baseline Results.

Am J Ophthalmol. 2024-1

[10]
New era after ChatGPT in ophthalmology: advances from data-based decision support to patient-centered generative artificial intelligence.

Ann Transl Med. 2023-8-30

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