Cytotoxic, antioxidant, antibacterial activity of phytochemicals from .

The cytotoxic, antioxidant, anticancer, and antibacterial properties of ethanolic extracts from is of interest. Plants of were gathered from the southern Saudi Arabian region of Albaha. extract was assessed using DPPH (2, 2-diphenyl-1-picrylhydrazyl). The German Collection of Microorganisms and Cell Cultures (DSMZ) cancer cell lines used in this investigation. The cytotoxic activity of extract was explored against MCF-7 breast and A549 lung cancer cell lines, along with doxorubicin as a positive control. In both treated cells, showed a remarkable activity suppressing the cell's survival. In terms of IC50 (concentration equivalent to a survival rate of 50%), MCF-7 breast cancer cells were more sensitive to extract.) DPPH colorimetric assay was employed to assess the antioxidant properties of extract, the antioxidant activity was increased along with increment of extract concentrations. The leaves aqueous extract of inhibited the growth of by 6.3±0.12 mm and 24±0.43 mm and 15±0.56 mm respectively for seed, leaf and stem at concentrations 50 µl. However, the same concentrations inhibited the growth of by 25±0.75, 0.00 mm and 24±0.18 mm, following the same order. Different superscript letters indicate means that are significantly different at level (p<0.05). Minimal inhibitory concentrations (MIC) of ethanolic extracts against the tested microorganisms were 1.5, 1.6 and 1.5, respectively for seed, leaf and stem against and were 1.2, 0.00 and 1.2, respectively for seed, leaf and stem against .