University of Oxford, Department of Oncology, Oxford, United Kingdom.
University of Dundee, School of Science and Engineering, United Kingdom.
J Biomed Opt. 2024 Aug;29(8):080801. doi: 10.1117/1.JBO.29.8.080801. Epub 2024 Aug 14.
Photoacoustic imaging (PAI) is an emerging technology that holds high promise in a wide range of clinical applications, but standardized methods for system testing are lacking, impeding objective device performance evaluation, calibration, and inter-device comparisons. To address this shortfall, this tutorial offers readers structured guidance in developing tissue-mimicking phantoms for photoacoustic applications with potential extensions to certain acoustic and optical imaging applications.
The tutorial review aims to summarize recommendations on phantom development for PAI applications to harmonize efforts in standardization and system calibration in the field.
The International Photoacoustic Standardization Consortium has conducted a consensus exercise to define recommendations for the development of tissue-mimicking phantoms in PAI.
Recommendations on phantom development are summarized in seven defined steps, expanding from (1) general understanding of the imaging modality, definition of (2) relevant terminology and parameters and (3) phantom purposes, recommendation of (4) basic material properties, (5) material characterization methods, and (6) phantom design to (7) reproducibility efforts.
The tutorial offers a comprehensive framework for the development of tissue-mimicking phantoms in PAI to streamline efforts in system testing and push forward the advancement and translation of the technology.
光声成像是一种新兴技术，在广泛的临床应用中具有很高的应用前景，但缺乏标准化的系统测试方法，这阻碍了客观的设备性能评估、校准和设备间的比较。为了弥补这一不足，本教程为读者提供了一种结构化的方法，用于开发用于光声应用的组织模拟体，其潜在的扩展可应用于某些声学和光学成像应用。
本教程综述旨在总结用于光声应用的成像体开发建议，以协调该领域的标准化和系统校准工作。
国际光声标准化联盟已进行了一项共识性工作，以定义用于光声成像的组织模拟体的开发建议。
总结了七个定义明确的成像体开发步骤，包括（1）对成像模式的一般理解、（2）相关术语和参数的定义、（3）成像体的目的、（4）基本材料特性的推荐、（5）材料特性的表征方法、（6）成像体设计以及（7）可重复性工作。
本教程为光声成像中组织模拟体的开发提供了一个全面的框架，以简化系统测试的工作，并推动该技术的发展和转化。
