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肠蠕虫病与巴西利什曼病扩散的关联。

Association of Intestinal Helminthiasis with Disseminated Leishmaniasis, Brazil.

出版信息

Emerg Infect Dis. 2024 Sep;30(9):1970-1972. doi: 10.3201/eid3009.240419.

DOI:10.3201/eid3009.240419
PMID:39174024
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11347011/
Abstract

Disseminated leishmaniasis is an emerging clinical form of Leishmania braziliensis infection. Evidence shows that co-infection by L. braziliensis and intestinal helminths does not affect clinical manifestations or response to therapy in cutaneous leishmaniasis patients. We evaluated whether co-infection was associated with those aspects in disseminated leishmaniasis patients in Brazil.

摘要

播散型利什曼病是巴西利什曼原虫感染的一种新兴临床形式。有证据表明，巴西利什曼原虫与肠道蠕虫的合并感染不会影响皮肤利什曼病患者的临床表现或治疗反应。我们评估了在巴西的播散型利什曼病患者中，合并感染是否与这些方面相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe76/11347011/832956bc954e/24-0419-F.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe76/11347011/832956bc954e/24-0419-F.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe76/11347011/832956bc954e/24-0419-F.jpg

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本文引用的文献

1
The Influence of Infection by Different Isolates on the Pathogenesis of Disseminated Leishmaniasis.不同分离株感染对播散性黑热病发病机制的影响。
Front Cell Infect Microbiol. 2021 Sep 10;11:740278. doi: 10.3389/fcimb.2021.740278. eCollection 2021.
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Influence of Intestinal Helminth Burden on Clinical Manifestations, Therapeutic Response, and Leishmania braziliensis Load in Patients with New World Cutaneous Leishmaniasis.肠道蠕虫负担对新世界皮肤利什曼病患者临床表现、治疗反应和巴西利什曼原虫负荷的影响。
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Intestinal helminth coinfection is associated with mucosal lesions and poor response to therapy in American tegumentary leishmaniasis.肠道蠕虫混合感染与美洲皮肤利什曼病的黏膜病变及治疗反应不佳有关。
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Association between an emerging disseminated form of leishmaniasis and Leishmania (Viannia) braziliensis strain polymorphisms.新型播散性利什曼病与利什曼原虫（Viannia）巴西利ensis 株多态性之间的关联。
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Reappraisal of the immunopathogenesis of disseminated leishmaniasis: in situ and systemic immune response.重新评估播散性利什曼病的免疫发病机制：原位和全身免疫反应。
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7
Antihelminthic therapy and antimony in cutaneous leishmaniasis: a randomized, double-blind, placebo-controlled trial in patients co-infected with helminths and Leishmania braziliensis.抗蠕虫治疗和皮肤利什曼病中的锑：在感染蠕虫和巴西利什曼原虫的患者中进行的随机、双盲、安慰剂对照试验。
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8
Influence of helminth infections on the clinical course of and immune response to Leishmania braziliensis cutaneous leishmaniasis.蠕虫感染对巴西利什曼原虫皮肤利什曼病临床病程及免疫反应的影响。
J Infect Dis. 2007 Jan 1;195(1):142-8. doi: 10.1086/509808. Epub 2006 Nov 22.
9
Disseminated leishmaniasis: a new and emerging form of leishmaniasis observed in northeastern Brazil.播散性利什曼病：巴西东北部发现的一种新出现的利什曼病形式。
J Infect Dis. 2002 Dec 15;186(12):1829-34. doi: 10.1086/345772. Epub 2002 Nov 19.