Smell and Taste Clinic, Department of Otorhinolaryngology, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Germany.
Department of Otolaryngology - Head and Neck Surgery, Asian Hospital and Medical Center, Muntinlupa, Philippines.
Eur Arch Otorhinolaryngol. 2024 Oct;281(10):5541-5547. doi: 10.1007/s00405-024-08900-w. Epub 2024 Aug 23.
This pilot study aimed to determine whether the Henkin olfactory test discriminates between the olfactory function of patients with olfactory loss and healthy individuals, and whether the Henkin test is correlated with a validated psychophysical olfactory test.
Participants underwent olfactory testing using the modified Henkin test (including detection [DT] and recognition [RT] thresholds, magnitude estimation [ME], and hedonic ratings [H], for four different odors) and the extended "Sniffin' Sticks" test battery (odor detection, discrimination, identification).
Forty-four individuals (28 women, aged 19-81 years, mean: 39 years) were included. Twenty-three were healthy (mean age: 38 years) and 21 had olfactory dysfunction (OD) (mean age: 40 years). OD patients had worse mean DT, lower composite RT, and lower ME ratings. Mean and individual odor H ratings were not significantly different between the groups. Most individuals were classified as hyposmic when using the prescribed classification by Henkin, with only very few satisfying the stringent criteria of anosmia and normosmia. Modified Henkin subtests were all positively correlated with each other and with the "Sniffin' Sticks", except for Unpleasant Mean H which was only correlated with Pleasant Mean H; and Pleasant mean H which was not correlated with mean DT scores.
The Henkin test is able to separate between OD patients and controls. However, modifications to the conduct of this test may be required. Studies that used this test should be carefully interpreted.
本初步研究旨在确定 Henkin 嗅觉测试是否能区分嗅觉丧失患者和健康个体的嗅觉功能，以及 Henkin 测试是否与经过验证的心理物理学嗅觉测试相关。
参与者接受了改良 Henkin 测试（包括检测 [DT] 和识别 [RT] 阈值、主观评分 [ME] 和愉悦评分 [H]，用于四种不同气味）和扩展的“Sniffin' Sticks”测试套件（嗅觉检测、辨别、识别）的嗅觉测试。
共有 44 人（28 名女性，年龄 19-81 岁，平均年龄：39 岁）参与了研究。其中 23 人健康（平均年龄：38 岁），21 人嗅觉功能障碍（OD）（平均年龄：40 岁）。OD 患者的平均 DT 更差，综合 RT 更低，ME 评分更低。两组的平均和个体气味 H 评分无显著差异。大多数个体根据 Henkin 规定的分类被归类为嗅觉减退，只有极少数符合嗅觉丧失和嗅觉正常的严格标准。改良 Henkin 子测试彼此之间以及与“Sniffin' Sticks”均呈正相关，除了不愉快平均 H 仅与愉快平均 H 相关，以及愉快平均 H 与平均 DT 评分不相关。
Henkin 测试能够区分 OD 患者和对照组。然而，可能需要对该测试的进行方式进行修改。使用该测试的研究应谨慎解释。
