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α-生育酚的包埋到玉米醇溶蛋白纳米粒中防止紫外线诱导降解。

Protection of α-Tocopherol from UV-Induced Degradation by Encapsulation into Zein Nanoparticles.

机构信息

Plant Polymer Research Unit, National Center for Agricultural Utilization Research, Agricultural Research Service, USDA, 1815 N. University Street, Peoria, IL 61604, USA.

出版信息

Molecules. 2024 Aug 19;29(16):3911. doi: 10.3390/molecules29163911.

DOI:10.3390/molecules29163911
PMID:39202990
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11356990/
Abstract

Vitamin E is a fat-soluble vitamin with several forms. Among these, α-tocopherol (TOC) is preferentially absorbed and accumulated in humans. In the body, it acts as an antioxidant, helping to protect cells from the damage caused by free radicals. It is an organic chemical compound that undergoes degradation upon irradiation with UV light. To protect this bioactive chemical compound from UV light degradation, encapsulation was carried out using zein as a shell material. Due to the unique phase diagram of TOC in aqueous ethanol, the encapsulation efficiency was >99%. The size of encapsulated particles was ~300 nm or smaller, and the thickness of the shell wall was ~30 nm. The presented procedure offers the most simple and efficient encapsulation process that yields edible products. The investigation of the irradiation effect of UV on TOC revealed that the encapsulation effectively blocks UV light and prevents TOC from being degraded. The presented procedure offers an instantaneous and highly efficient encapsulation process, which yields edible products.

摘要

维生素 E 是一种脂溶性维生素,有多种形式。其中,α-生育酚(TOC)在人体中优先被吸收和积累。在体内,它作为一种抗氧化剂,有助于保护细胞免受自由基的损伤。它是一种有机化合物,在受到紫外线照射时会发生降解。为了防止这种生物活性化学物质因紫外线降解,采用玉米醇溶蛋白作为壳材料进行包封。由于 TOC 在水-乙醇中的独特相图,包封效率>99%。包封颗粒的大小约为 300nm 或更小,壳壁的厚度约为 30nm。所提出的方法提供了最简单、最有效的包封工艺,可得到可食用的产品。对 TOC 受紫外线照射的影响的研究表明,包封能有效地阻挡紫外线,防止 TOC 降解。所提出的方法提供了一种瞬时的、高效的包封工艺,可得到可食用的产品。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d1/11356990/19e392f746bc/molecules-29-03911-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d1/11356990/0f372b569b31/molecules-29-03911-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d1/11356990/d39adf28c295/molecules-29-03911-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d1/11356990/3f8fd277846c/molecules-29-03911-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d1/11356990/370d08dcdc7e/molecules-29-03911-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d1/11356990/fcb634469e3e/molecules-29-03911-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d1/11356990/84c17f700ff4/molecules-29-03911-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d1/11356990/19e392f746bc/molecules-29-03911-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d1/11356990/0f372b569b31/molecules-29-03911-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d1/11356990/d39adf28c295/molecules-29-03911-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d1/11356990/3f8fd277846c/molecules-29-03911-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d1/11356990/370d08dcdc7e/molecules-29-03911-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d1/11356990/fcb634469e3e/molecules-29-03911-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d1/11356990/84c17f700ff4/molecules-29-03911-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2d1/11356990/19e392f746bc/molecules-29-03911-g007.jpg

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