Department of Information Engineering, Electronics and Telecommunications, Sapienza University of Rome, 00184 Rome, Italy.
Department of Chemical Engineering Materials Environment, Sapienza University of Rome, 00161 Rome, Italy.
Sensors (Basel). 2024 Aug 18;24(16):5338. doi: 10.3390/s24165338.
Several medical techniques are based on the application of electromagnetic fields (EMFs) on the human body with therapeutic and/or diagnostic aims. The response of human tissues to the applied EMF is mediated by the tissues' dielectric properties, which must therefore be characterized at the frequencies of the considered technique. Due to the heterogeneity and complexity of biological tissues, it is necessary to know their properties in vivo for the specific condition of interest. Traditional techniques for the dielectric characterization of biological tissues are invasive and, as such, not adoptable for this aim. Accordingly, alternative sensors and/or sensing methods are needed. Recently, a new wideband spectroscopy technique was proposed, based on quantities derived from the Magnetic Resonance (MRI) signal. Among these quantities, the water content was proposed to evaluate the dielectric properties at frequencies around a few GHz. This work verifies the possibility of deriving tissues' dielectric properties in the frequency range of 1-20 GHz based on knowledge of the water content. The water content was retrieved through a dehydration procedure for five different ex vivo tissues. The achieved results were compared with references from the literature.
几种医学技术都是基于将电磁场 (EMF) 应用于人体,以达到治疗和/或诊断的目的。人体组织对所施加的电磁场的反应是由组织的介电特性介导的,因此必须在考虑的技术频率下对其进行特性描述。由于生物组织的不均匀性和复杂性,有必要了解其在体内的特性,以达到感兴趣的特定条件。传统的生物组织介电特性的表征技术是侵入性的,因此不适合这一目的。因此,需要替代的传感器和/或传感方法。最近,提出了一种基于从磁共振(MRI)信号中得出的量的新的宽带光谱技术。在这些量中,提出了水含量来评估几 GHz 左右频率的介电特性。这项工作验证了基于水含量知识来推导组织在 1-20GHz 频率范围内的介电特性的可能性。水含量是通过对五种不同的离体组织进行脱水过程来获取的。所得到的结果与文献中的参考值进行了比较。