Hottinguer-De Margerie H, Moustacchi E
Mol Gen Genet. 1979 Oct 1;175(3):259-65. doi: 10.1007/BF00397225.
The response to ultraviolet light (254 nm) of two sporulation mutants during the meiotic process was compared to that of a wild type diploid strain of Saccharomyces cerevisiae. The cyclic pattern for cell killing and rho- induction characteristic of diploid wild type cells persists in a strain able to perform the premeiotic DNA synthesis but which is blocked in the further steps of meiosis (spo8 DMS1). On the contrary, these fluctations are abolished in a derived mutant (spo8 dsm1) which is blocked in the premeiotic DNA synthesis. Under these conditions, the response to cell killing can be dissociated from the observed for rho- induction.
将酿酒酵母的两个孢子形成突变体在减数分裂过程中对紫外线（254纳米）的反应与野生型二倍体菌株的反应进行了比较。能够进行减数分裂前DNA合成但在减数分裂后续步骤中受阻的菌株（spo8 DMS1），保留了二倍体野生型细胞特有的细胞杀伤和ρ诱导的循环模式。相反，在减数分裂前DNA合成受阻的衍生突变体（spo8 dsm1）中，这些波动消失了。在这些条件下，细胞杀伤反应与观察到的ρ诱导反应可以分离。
