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口腔癌高危人群的早期识别——现有风险预测模型综述

Early identification of people at high risk of oral cancer-A review of existing risk prediction models.

作者信息

Mocherla Monica, Krishnappa Pushpanjali

机构信息

Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, Mathikere, Bengaluru, Karnataka, India.

Department of Public Health Dentistry, M. S. Ramaiah Dental College and Hospital, M. S. Ramaiah University of Applied Sciences, Mathikere, Bengaluru, Karnataka, India.

出版信息

J Family Med Prim Care. 2024 Aug;13(8):2851-2856. doi: 10.4103/jfmpc.jfmpc_117_24. Epub 2024 Jul 26.

Abstract

Prediction plays a ubiquitous role in cancer care. At every stage of the illness, the patient, the physician, and the family must make numerous decisions. Utilizing epidemiological, clinical, biological, lifestyle, and genetic factors, a cancer-specific risk assessment model calculates the likelihood of developing cancer. In India, oral cancer ranks as the fourth most common cancer, affecting nearly 3,000,00 individuals annually. Because it is in the premalignant stage, oral cancer is easily detectable in the oral cavity. Prompt identification of this lesion can result in better outcomes and a higher standard of living. Advanced statistical techniques have been used to develop prediction algorithms or risk scores that identify individuals with a high risk of developing oral cancer. With the aid of these risk assessment models, specific individuals can be screened to aid in the early detection of the disease, which may result in better outcomes and lifestyle modifications. Finding the best model among the current risk models for oral cancer may be aided by a thorough examination of all these models. Finding and assessing the risk model that primary care physicians can use and easily apply in clinical practice will be made easier with a succinct and straightforward comparison of the models. This review compares the current models to determine which has the best performance metrics, which could lead to a better understanding of the advantages and disadvantages of various risk prediction models of oral cancer.

摘要

预测在癌症治疗中起着普遍作用。在疾病的每个阶段,患者、医生和家属都必须做出众多决策。癌症特异性风险评估模型利用流行病学、临床、生物学、生活方式和遗传因素来计算患癌的可能性。在印度,口腔癌是第四大常见癌症,每年影响近300万人。由于处于癌前阶段,口腔癌在口腔中很容易被检测到。及时识别这种病变可带来更好的治疗效果和更高的生活水平。先进的统计技术已被用于开发预测算法或风险评分,以识别患口腔癌风险高的个体。借助这些风险评估模型,可以对特定个体进行筛查,以帮助早期发现疾病,这可能带来更好的治疗效果和生活方式的改变。对所有这些模型进行全面检查,可能有助于在当前的口腔癌风险模型中找到最佳模型。通过对模型进行简洁明了的比较,将更容易找到并评估基层医疗医生可以在临床实践中使用并轻松应用的风险模型。本综述比较了当前的模型,以确定哪种模型具有最佳的性能指标,这可能有助于更好地理解各种口腔癌风险预测模型的优缺点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d0e/11368278/e92cb99a1f5b/JFMPC-13-2851-g001.jpg

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