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遗传多态性与外部根尖吸收研究文献的计量分析。

Bibliometric analysis of publications on genetic polymorphism and external apical root resorption research.

机构信息

Fluminense Federal University, Postgraduate Program in Dentistry (Niterói/RJ, Brazil).

Fluminense Federal University, Nova Friburgo Institute of Health, School of Biomedicine (Nova Friburgo/RJ, Brazil).

出版信息

Dental Press J Orthod. 2024 Sep 2;29(4):e2423268. doi: 10.1590/2177-6709.29.4.e2423268.oar. eCollection 2024.

DOI:10.1590/2177-6709.29.4.e2423268.oar
PMID:39230110
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11368243/
Abstract

OBJECTIVE

This study aimed to analyze the scientific production of genetic polymorphisms and external apical root resorption (EARR) to establish main findings, geographic trends, and research gaps for possible future investigations.

METHODS

Unrestricted publications were searched using the Scopus database (March 2023) to include studies that addressed the association between genetic polymorphisms and EARR. Case-control, cohort, cross-sectional, and review studies were considered eligible. The softwares VOS viewer™ and Bibliometrix were used for data analysis.

RESULTS

Of the 44 studies analyzed, "Iglesias-Linares A" was the most cited author. The University of Seville (Spain) conducted the most research on this topic. Brazil, Spain, and the USA were the leading countries in terms of citations. The most frequent term in the co-occurrence of keywords was "EARR." The journal American Journal of Orthodontics and Dentofacial Orthopedics presented a great relevance in the area, demonstrating a high number of publications. Several genetic polymorphisms have been investigated, with interleukins being the most studied.

CONCLUSION

Endodontics is an area of research that should focus more on root resorption and genetic polymorphisms, as it still underexplored, compared to orthodontics. Polymorphisms have been studied as possible predictors of EARR caused by orthodontic tooth movement. However, the gap in the research indicates a need to search for new genes associated with EARR.

摘要

目的

本研究旨在分析遗传多态性与外部根尖吸收（EARR）的科学研究成果，以确定主要发现、地理趋势和研究空白，为未来的研究提供参考。

方法

使用 Scopus 数据库（2023 年 3 月）进行无限制检索，以纳入探讨遗传多态性与 EARR 之间关联的研究。合格的研究包括病例对照、队列、横断面和综述研究。使用 VOS viewerTM 和 Bibliometrix 软件进行数据分析。

结果

在分析的 44 项研究中，“Iglesias-Linares A”是被引用最多的作者。塞维利亚大学（西班牙）在该主题上进行了最多的研究。巴西、西班牙和美国在引文方面处于领先地位。关键词共现最频繁的术语是“EARR”。《美国口腔正畸学和口腔颌面正畸学杂志》在该领域具有重要意义，显示出大量的出版物。已经研究了几种遗传多态性，其中白细胞介素是研究最多的。

结论

与口腔正畸学相比，牙髓学是一个研究相对较少的领域，应该更加关注根吸收和遗传多态性。多态性已被研究为正畸牙移动引起的 EARR 的可能预测因子。然而，研究中的空白表明需要寻找与 EARR 相关的新基因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c71/11368243/3afc7ca35edc/2177-6709-dpjo-29-04-e2423268-gf9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c71/11368243/23742fe0affe/2177-6709-dpjo-29-04-e2423268-gf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c71/11368243/ea9feb20efd5/2177-6709-dpjo-29-04-e2423268-gf2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c71/11368243/f0109919f62b/2177-6709-dpjo-29-04-e2423268-gf3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c71/11368243/09108b6a221f/2177-6709-dpjo-29-04-e2423268-gf4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c71/11368243/8f22d2deca17/2177-6709-dpjo-29-04-e2423268-gf5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c71/11368243/021ccf6ac24e/2177-6709-dpjo-29-04-e2423268-gf6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c71/11368243/80e8a44b1083/2177-6709-dpjo-29-04-e2423268-gf7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c71/11368243/99026ef4cdc4/2177-6709-dpjo-29-04-e2423268-gf8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c71/11368243/3afc7ca35edc/2177-6709-dpjo-29-04-e2423268-gf9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c71/11368243/23742fe0affe/2177-6709-dpjo-29-04-e2423268-gf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c71/11368243/ea9feb20efd5/2177-6709-dpjo-29-04-e2423268-gf2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c71/11368243/f0109919f62b/2177-6709-dpjo-29-04-e2423268-gf3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c71/11368243/09108b6a221f/2177-6709-dpjo-29-04-e2423268-gf4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c71/11368243/8f22d2deca17/2177-6709-dpjo-29-04-e2423268-gf5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c71/11368243/021ccf6ac24e/2177-6709-dpjo-29-04-e2423268-gf6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c71/11368243/80e8a44b1083/2177-6709-dpjo-29-04-e2423268-gf7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c71/11368243/99026ef4cdc4/2177-6709-dpjo-29-04-e2423268-gf8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c71/11368243/3afc7ca35edc/2177-6709-dpjo-29-04-e2423268-gf9.jpg

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Eur J Oral Sci. 2023 Apr;131(2):e12916. doi: 10.1111/eos.12916. Epub 2023 Jan 22.
3
Targeted next-generation sequencing for comprehensive genetic analysis of external apical root resorption during orthodontic treatment with premolar extraction in the Korean population.
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Am J Orthod Dentofacial Orthop. 2022 Nov;162(5):668-679.e5. doi: 10.1016/j.ajodo.2021.06.022. Epub 2022 Aug 11.
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Influence of clinical factors on the protective or deleterious impact of genetic variants in orthodontically induced external root resorption: an observational study.临床因素对正畸诱导性牙根外吸收中遗传变异的保护或有害影响的影响：一项观察性研究。
BMC Oral Health. 2022 Jul 4;22(1):270. doi: 10.1186/s12903-022-02306-y.
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Influence of clinical factors, IL4 and IL6 genes polymorphisms in functional healing in late replantation.临床因素、IL4 和 IL6 基因多态性对晚期再植功能愈合的影响。
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