Lau Meng Fei, Phan Chia Wei, Sabaratnam Vikineswary, Kuppusamy Umah Rani
Department of Biomedical Sciences, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Mushroom Research Centre, Universiti Malaya, Kuala Lumpur, Malaysia.
Mycology. 2024 Jan 21;15(3):360-373. doi: 10.1080/21501203.2024.2302028. eCollection 2024.
, a traditional medicine in Asian countries, has been used to prevent and treat various ailments for centuries. (synonym ), also known as purple Lingzhi, is a species that is currently underutilised when compared to (Lingzhi). However, in recent decades, this mushroom has garnered significant attention due to its ethnomedicinal uses, especially in Southeast Asia regions like Malaysia. The taxonomy and nomenclature of this mushroom have been extensively studied. Numerous publications have reported that displays a variety of medicinal properties, including antioxidation, anticancer, anti-hyperglycaemic, genoprotective, hepatoprotective, neuritogenic, and antidiabetic effects, both and . With the surge of research findings on this mushroom, this review aims to provide a systematic bibliometric analysis of , published between 1991 to 2021. Additionally, the taxonomic description of this mushroom is discussed in detail. Our review reveals that contains polysaccharides (α/β-D-glucans), triterpenoids, and sterols/ergosterol. However, the existing literature suggests that these active compounds have not yet been explored to their full potential as drug candidates. Moreover, most of the studies are preclinical and have several drawbacks. In conclusion, possesses valuable pharmacological activities that merit further exploration.
在亚洲国家作为传统药物,已被用于预防和治疗各种疾病达数百年之久。(同义词),也被称为紫灵芝,与(灵芝)相比,是一种目前未得到充分利用的物种。然而,近几十年来,这种蘑菇因其民族药用价值,特别是在马来西亚等东南亚地区,受到了极大关注。这种蘑菇的分类学和命名法已得到广泛研究。众多出版物报道显示出多种药用特性,包括抗氧化、抗癌、抗高血糖、基因保护、肝脏保护、促神经突生长和抗糖尿病作用,体内和体外实验均有体现。随着关于这种蘑菇的研究结果激增,本综述旨在对1991年至2021年间发表的关于的文献进行系统的文献计量分析。此外,还详细讨论了这种蘑菇的分类学描述。我们的综述表明含有多糖(α/β - D - 葡聚糖)、三萜类化合物和甾醇/麦角甾醇。然而,现有文献表明这些活性化合物作为候选药物的潜力尚未得到充分探索。此外,大多数研究是临床前研究,存在一些缺陷。总之,具有值得进一步探索的有价值的药理活性。