Shehbaz Amna, Afzaal Muhammad, Akram Noor, Saeed Farhan, Khan Warda, Ahmed Faiyaz, Ahmed Aftab, Asghar Aasma, Faisal Zargham
Department of Food Science, Government College University Faisalabad, Faisalabad, Pakistan.
Food Safety & Biotechnology Lab, Department of Food Science, Government College University Faisalabad, Faisalabad, Pakistan.
Probiotics Antimicrob Proteins. 2025 Feb;17(1):479-486. doi: 10.1007/s12602-024-10358-5. Epub 2024 Sep 11.
Intermittent fasting (IF) is an increasingly popular dietary approach involving alternating fasting and eating periods. This review aims to summarize the growing body of literature demonstrating that IF is a potential nutritional practice that involves alternating periods of fasting and eating and the numerous benefits of IF, especially in the modulation of healthy gut microbiota. The positive impact of intermittent fasting on gut microbiota not only promotes gastrointestinal health but also has far-reaching effects on critical systems throughout the body. Additionally, the evidence presented in this review highlights the significant preventive and therapeutic effects of intermittent fasting on a wide range of disorders. This includes reducing the risk of diabetes, and neurological disorders, alleviating obesity, and enhancing the functioning of the liver, ultimately contributing to the maintenance of metabolic equilibrium. Perhaps most notably, these effects play a substantial role in preventing diabetes, a global health concern of increasing significance. This comprehensive investigation delves into the scientific foundations of intermittent fasting's impact on gut microbiota and its implications for averting chronic diseases, providing valuable insights for future research and therapeutic applications.
间歇性禁食（IF）是一种越来越流行的饮食方式，包括交替进行禁食和进食阶段。本综述旨在总结越来越多的文献，这些文献表明间歇性禁食是一种潜在的营养实践，涉及禁食和进食阶段的交替，以及间歇性禁食的诸多益处，特别是在调节健康的肠道微生物群方面。间歇性禁食对肠道微生物群的积极影响不仅促进胃肠道健康，而且对全身的关键系统也有深远影响。此外，本综述中呈现的证据突出了间歇性禁食对多种疾病的显著预防和治疗作用。这包括降低糖尿病和神经系统疾病的风险、减轻肥胖以及增强肝脏功能，最终有助于维持代谢平衡。也许最值得注意的是，这些作用在预防糖尿病方面发挥了重要作用，糖尿病是一个全球健康问题，其重要性日益增加。这项全面的调查深入探讨了间歇性禁食对肠道微生物群影响的科学基础及其对预防慢性病的意义，为未来的研究和治疗应用提供了有价值的见解。
