Fraser P, Booth M, Beral V, Inskip H, Firsht S, Speak S
Br Med J (Clin Res Ed). 1985 Aug 17;291(6493):435-9. doi: 10.1136/bmj.291.6493.435.
The United Kingdom Atomic Energy Authority mortality study investigated the relation between mortality and recorded exposure to ionising radiation among employees working at the authority's seven establishments between 1946 and 1979. This report examines the design of the study and methods of data collection and validation. The completeness of the study population was deemed to be unsatisfactory at two establishments, where records of employment before 1965 had been destroyed. Assessment of the magnitude of the deficit led to the conclusion that the data from these establishments were too incomplete for inclusion in the mortality analysis. At the other establishments validation showed that the data collected were accurate and unbiased. Certain characteristics of the 39 546 employees included in the mortality analysis were identified which were relevant in interpreting the findings.
英国原子能管理局死亡率研究调查了1946年至1979年间在该管理局七个机构工作的员工死亡率与记录的电离辐射暴露之间的关系。本报告审视了该研究的设计以及数据收集和验证方法。在两个机构中,研究人群的完整性被认为不令人满意,因为1965年之前的就业记录已被销毁。对缺失规模的评估得出结论,来自这些机构的数据过于不完整,无法纳入死亡率分析。在其他机构,验证表明所收集的数据准确且无偏差。确定了纳入死亡率分析的39546名员工的某些特征,这些特征在解释研究结果时具有相关性。