Yang Haiqiong, Gao Jiali, Zheng Zaiyong, Yu Yang, Zhang Chunxiang
Department of Cardiology, The Affiliated Hospital, Southwest Medical University, Luzhou, China.
Key Laboratory of Medical Electrophysiology, Ministry of Education & Medical Electrophysiological Key Laboratory of Sichuan Province, (Collaborative Innovation Center for Prevention of Cardiovascular Diseases), Institute of Cardiovascular Research, Southwest Medical University, Luzhou, China.
Heliyon. 2024 Aug 22;10(17):e36681. doi: 10.1016/j.heliyon.2024.e36681. eCollection 2024 Sep 15.
Non-coding RNAs have emerged as important regulators of gene expression and contributors to many diseases. LncRNA Morrbid, a long non-coding RNA, has been widely studied in recent years. Current literature reports that lncRNA Morrbid is involved in various diseases such as tumors, cardiovascular diseases, inflammatory diseases and metabolic disorder. However, controversial conclusions exist in current studies. As a potential therapeutic target, it is necessary to comprehensively review the current evidence. In this work, we carefully review the literature on Morrbid and discuss each of the hot topics related to lncRNA Morrbid.
非编码RNA已成为基因表达的重要调节因子，并与许多疾病的发生有关。长链非编码RNA Morrbid近年来受到广泛研究。目前的文献报道，lncRNA Morrbid参与了肿瘤、心血管疾病、炎症性疾病和代谢紊乱等多种疾病。然而，目前的研究存在争议性结论。作为一个潜在的治疗靶点，有必要全面回顾当前的证据。在这项工作中，我们仔细回顾了关于Morrbid的文献，并讨论了与lncRNA Morrbid相关的每个热点话题。
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