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多氯联苯变压器或电容器事故后,对接触多氯联苯、氯代二苯并二恶英和二苯并呋喃的人员进行医学监测。

Medical surveillance of exposed persons after exposure to PCBs, chlorinated dibenzodioxins and dibenzofurans after PCB transformer or capacitor incidents.

作者信息

Schecter A

出版信息

Environ Health Perspect. 1985 May;60:333-8. doi: 10.1289/ehp.8560333.

DOI:10.1289/ehp.8560333
PMID:3928362
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1568580/
Abstract

The panel discussion from the perspective of occupational medicine regarding appropriate medical surveillance after a PCB transformer or capacitor incident is reviewed. A thorough occupational medicine history and physical examination is stressed for any worker or other patient who may have been exposed. Appropriate laboratory tests, including complete blood count with differential, serum chemistries, serial blood PCB determinations, fat biopsy to estimate furan and dioxin levels, if indicated, pulmonary function tests, chest X-rays, urinalysis including porphyrin measurement, nerve conduction velocity testing and other tests are discussed. No consensus was reached on recommended length of medical followup. Because the field is rapidly changing, yearly updates of medical protocols are warranted. In addition, the need for surveillance to be conducted by specialists with training and experience in the fields of occupational medicine and nursing was emphasized. It was stressed that measuring the chemicals and their levels in soot and air and then comparing these with the patient's blood or fat levels, in the case of PCBs, furans and dioxins, is vital. It was noted that at present no modality of treatment is known to be clinically efficacious in removing PCBs, furans and dioxins from tissues or blood.

摘要

本文回顾了职业医学领域关于多氯联苯(PCB)变压器或电容器事故后适当医学监测的小组讨论。对于任何可能接触过的工人或其他患者,强调要进行全面的职业医学病史采集和体格检查。讨论了适当的实验室检查,包括血常规及分类、血清化学检查、连续血液多氯联苯测定、必要时进行脂肪活检以估计呋喃和二噁英水平、肺功能测试、胸部X光检查、包括卟啉测量的尿液分析、神经传导速度测试及其他检查。对于推荐的医学随访时长未达成共识。由于该领域变化迅速,医学方案需要每年更新。此外,强调需要由在职业医学和护理领域接受过培训且有经验的专家进行监测。有人强调,对于多氯联苯、呋喃和二噁英,测量烟尘和空气中的化学物质及其水平,然后将这些与患者的血液或脂肪水平进行比较至关重要。有人指出,目前尚无已知的临床有效治疗方法可从组织或血液中清除多氯联苯、呋喃和二噁英。

相似文献

1
Medical surveillance of exposed persons after exposure to PCBs, chlorinated dibenzodioxins and dibenzofurans after PCB transformer or capacitor incidents.多氯联苯变压器或电容器事故后,对接触多氯联苯、氯代二苯并二恶英和二苯并呋喃的人员进行医学监测。
Environ Health Perspect. 1985 May;60:333-8. doi: 10.1289/ehp.8560333.
2
Patient fat biopsies for chemical analysis and liver biopsies for ultrastructural characterization after exposure to polychlorinated dioxins, furans and PCBs.接触多氯二噁英、呋喃和多氯联苯后,取患者脂肪活检样本进行化学分析,并取肝脏活检样本进行超微结构特征分析。
Environ Health Perspect. 1985 May;60:241-54. doi: 10.1289/ehp.8560241.
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Occupational exposure to polychlorinated dioxins, polychlorinated furans, polychlorinated biphenyls, and biphenylenes after an electrical panel and transformer accident in an office building in Binghamton, NY.纽约宾厄姆顿一座办公楼发生电气面板和变压器事故后,职业性接触多氯二噁英、多氯呋喃、多氯联苯和联苯撑。
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Health effects three years after potential exposure to the toxic contaminants of an electrical transformer fire.接触变压器火灾产生的有毒污染物三年后的健康影响。
Arch Environ Health. 1989 Jul-Aug;44(4):214-21. doi: 10.1080/00039896.1989.9935886.
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Assessment of health effects in New York City firefighters after exposure to polychlorinated biphenyls (PCBs) and polychlorinated dibenzofurans (PCDFs): the Staten Island Transformer Fire Health Surveillance Project.纽约市消防员接触多氯联苯(PCBs)和多氯二苯并呋喃(PCDFs)后健康影响评估:斯塔滕岛变压器火灾健康监测项目。
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Formation, occurrence and analysis of polychlorinated dibenzofurans, dioxins and related compounds.多氯二苯并呋喃、二噁英及相关化合物的形成、存在与分析
Environ Health Perspect. 1985 May;60:259-67. doi: 10.1289/ehp.8560259.
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Assessing the health effects of potential exposure to PCBs, dioxins, and furans from electrical transformer fires: the Binghamton State Office Building medical surveillance program.评估因变压器火灾潜在接触多氯联苯、二噁英和呋喃对健康的影响:宾厄姆顿州政府办公楼医疗监测项目
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Formation of polychlorinated dibenzofurans and dioxins during combustion, electrical equipment fires and PCB incineration.燃烧、电气设备火灾及多氯联苯焚烧过程中多氯二苯并呋喃和二噁英的形成。
Environ Health Perspect. 1985 May;60:3-9. doi: 10.1289/ehp.85603.
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Polychlorinated biphenyl (PCB) and dichlorodiphenyl dichloroethylene (DDE) exposure among Native American men from contaminated Great Lakes fish and wildlife.来自受污染的五大湖鱼类和野生动物的美国原住民男性体内多氯联苯(PCB)和二氯二苯二氯乙烯(DDE)的暴露情况。
Toxicol Ind Health. 1996 May-Aug;12(3-4):361-8. doi: 10.1177/074823379601200308.
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Health risks to infants from exposure to PCBs, PCDDs and PCDFs.婴儿接触多氯联苯、多氯二苯并二恶英和多氯二苯并呋喃所面临的健康风险。
Food Addit Contam. 2000 Apr;17(4):325-33. doi: 10.1080/026520300283397.

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