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孤立性颈外静脉血栓性静脉炎继发于急性咽炎:病例报告及文献复习。

Isolated external jugular thrombophlebitis secondary to acute pharyngitis: a case report and a review of the literature.

机构信息

Division of Pediatric Otolaryngology, Department of Otolaryngology Head and Neck Surgery, NYU Langone Health, 240 East 38th Street 14th floor, New York, NY, 10016, USA.

Department of Pediatrics, Hassenfeld Children's Hospital at NYU Langone Health, New York, NY, USA.

出版信息

Ital J Pediatr. 2024 Sep 16;50(1):179. doi: 10.1186/s13052-024-01760-4.

Abstract

BACKGROUND

External Jugular Thrombophlebitis (EJT) is a rare clinical phenomenon with few reports in the literature, especially in the pediatric population. This is a report of an unusual case of right-sided EJT in a pediatric patient secondary to acute pharyngitis with sinusitis most prominent on the left side.

CASE PRESENTATION

A 13-year-old presented to the emergency department with worsening upper respiratory infectious (URI) symptoms and facial swelling, cough, throat pain, and emesis. The patient had traveled to Switzerland and received amoxicillin for strep throat 6 weeks before this hospitalization. Physical examination revealed nasal purulence, allodynia over the right side of the face without overlying erythema, and oropharyngeal exudate. CT scan revealed left-sided predominate sinusitis and right external jugular vein thrombosis. Blood cultures confirmed the presence of group A streptococcus infection. Treatment included IV antibiotics, non-steroidal anti-inflammatory drugs (NSAIDs), IV steroids, and anticoagulation. Follow-up imaging demonstrated improvement in thrombosis, cellulitis, and sinus disease. The patient was discharged on antibiotics for 6 weeks and anticoagulation for 10 weeks. Follow-up imaging at 6 months revealed no EJT, and medications were discontinued.

CONCLUSIONS

EJT is a rare condition, and to our knowledge, no reports of EJT with sinusitis most pronounced on the contralateral side have been published. Physicians will benefit from noting clinical signs of EJT such as facial edema, headache, erythema, and palpable neck mass, especially if these symptoms occur with URI symptoms refractory to treatment. The use of anticoagulation is controversial for internal jugular vein thrombosis, and while no guidelines for EJT exist, anticoagulation is likely not necessary save for severe complications.

摘要

背景

颈外静脉血栓形成(EJT)是一种罕见的临床现象,文献报道较少,尤其是在儿科人群中。这是一例儿童右侧 EJT 的不寻常病例,继发于左侧更为明显的急性咽炎伴鼻窦炎。

病例介绍

一名 13 岁患者因上呼吸道感染(URI)症状加重和面部肿胀、咳嗽、喉咙痛和呕吐而到急诊科就诊。该患者曾前往瑞士,并在此次住院前 6 周因链球菌性咽炎接受阿莫西林治疗。体格检查显示鼻腔脓性分泌物,右侧面部触痛,但无红斑,口咽渗出物。CT 扫描显示左侧为主的鼻窦炎和右侧颈外静脉血栓形成。血培养证实存在 A 组链球菌感染。治疗包括静脉注射抗生素、非甾体抗炎药(NSAIDs)、静脉注射类固醇和抗凝治疗。随访影像学显示血栓、蜂窝织炎和窦病均有所改善。患者接受 6 周抗生素和 10 周抗凝治疗后出院。6 个月的随访影像学显示无 EJT,停用药物。

结论

EJT 是一种罕见的疾病,据我们所知,尚无 EJT 伴对侧更为明显鼻窦炎的报道。如果这些症状与 URI 症状治疗无效同时出现,医生应注意 EJT 的临床体征,如面部水肿、头痛、红斑和可触及的颈部肿块。尽管没有针对 EJT 的指南,但对颈内静脉血栓形成使用抗凝治疗存在争议,除了严重并发症外,抗凝治疗可能并非必需。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/434d/11406880/7f213c7cd2c4/13052_2024_1760_Fig1_HTML.jpg

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