Shekoohi Niloofar, Carson Brian P, Fitzgerald Richard J
Department of Biological Sciences, University of Limerick, V94 T9PX Limerick, Ireland.
Department of Physical Education and Sport Sciences, Faculty of Education and Health Sciences, University of Limerick, V94 T9PX Limerick, Ireland.
J Agric Food Chem. 2024 Oct 2;72(39):21301-21317. doi: 10.1021/acs.jafc.4c02920. Epub 2024 Sep 19.
The marine environment is an excellent source for many physiologically active compounds due to its extensive biodiversity. Among these, fish proteins stand out for their unique qualities, making them valuable in a variety of applications due to their diverse compositional and functional properties. Utilizing fish and fish coproducts for the production of protein hydrolysates and bioactive peptides not only enhances their economic value but also reduces their potential environmental harm, if left unutilized. Fish protein hydrolysates (FPHs), known for their excellent nutritional value, favorable amino acid profiles, and beneficial biological activities, have generated significant interest for their potential health benefits. These hydrolysates contain bioactive peptides which are peptide sequences known for their beneficial physiological effects. These biologically active peptides play a role in metabolic regulation/modulation and are increasingly seen as promising ingredients in functional foods, nutraceuticals and pharmaceuticals, with potential to improve human health and prevent disease. This review aims to summarize the current , cell model () and research on the antioxidant, glycaemic management and muscle health enhancement properties of FPHs and their peptides.
由于海洋环境具有广泛的生物多样性，它是许多生理活性化合物的优质来源。其中，鱼类蛋白质因其独特的品质而脱颖而出，由于其多样的组成和功能特性，使其在各种应用中具有价值。利用鱼类及其副产物生产蛋白质水解物和生物活性肽，不仅提高了它们的经济价值，而且如果不加以利用，还会减少它们对环境的潜在危害。鱼类蛋白质水解物（FPHs）以其优异的营养价值、良好的氨基酸谱和有益的生物活性而闻名，因其潜在的健康益处而引起了人们的极大兴趣。这些水解物含有生物活性肽，这些肽序列因其有益的生理作用而闻名。这些生物活性肽在代谢调节/调控中发挥作用，并且越来越被视为功能性食品、营养保健品和药品中的有前景成分，具有改善人类健康和预防疾病的潜力。本综述旨在总结目前关于FPHs及其肽的抗氧化、血糖管理和增强肌肉健康特性的体外、细胞模型（）和体内研究。
