Department of Chemistry, Faculty of Science, Islamic University of Madinah, 42351, Madinah, Saudi Arabia.
Department of Bee Research, Agricultural Research Centre, Plant Protection Research Institute, Giza, 12627, Egypt.
Curr Nutr Rep. 2024 Dec;13(4):751-767. doi: 10.1007/s13668-024-00567-3. Epub 2024 Sep 20.
Diabetes and obesity are complicated multifactorial conditions that have been highlighted as a significant global burden for both health care and national budgets and their complications are considered a substantial public health concern. This review focuses on the potential anti-diabetic and anti-obesity properties of bee pollen (BP) and bee bread (BB), two bee products with a long history of use in traditional medicine and supplemental nutrition.
Recent studies, encompassing cellular models, experimental models, and clinical trials, have shed light on the therapeutic potential of these bee products. BP and BB are rich in phytochemical constituents like flavonoids and phenolic acids, which are believed to confer their anti-oxidant, anti-inflammatory, anti-cancer, anti-diabetic, and anti-obesity properties. These bee products have shown promising results in the treatment of diabetes and obesity, underscoring their potential as natural therapeutic tools. BP and BB possess properties that aid in decreasing blood glucose levels and body weight. BP and BB have been found to enhance insulin sensitivity, alleviate oxidative stress, regulate appetite, adjust levels of hormones linked to obesity, while bolstering anti-oxidant defense systems. BP and BB nutritional qualities and health benefits make them promising candidates for further research towards diabetes and obesity treatment strategies.
糖尿病和肥胖是复杂的多因素疾病，已成为全球医疗保健和国家预算的重大负担，其并发症被认为是一个重大的公共卫生问题。本综述重点介绍了蜂花粉（BP）和蜂粮（BB）这两种蜜蜂产品的潜在抗糖尿病和抗肥胖特性。这些蜜蜂产品在传统医学和补充营养方面有着悠久的使用历史。
最近的研究，包括细胞模型、实验模型和临床试验，揭示了这些蜜蜂产品的治疗潜力。BP 和 BB 富含类黄酮和酚酸等植物化学物质，这些物质被认为具有抗氧化、抗炎、抗癌、抗糖尿病和抗肥胖的特性。这些蜜蜂产品在糖尿病和肥胖的治疗中显示出了有希望的结果，强调了它们作为天然治疗工具的潜力。BP 和 BB 具有降低血糖水平和体重的特性。已经发现 BP 和 BB 可以提高胰岛素敏感性，减轻氧化应激，调节食欲，调节与肥胖相关的激素水平，同时增强抗氧化防御系统。BP 和 BB 的营养品质和健康益处使它们成为进一步研究糖尿病和肥胖治疗策略的有前途的候选者。
