Kjellén G, Tibbling L
Scand J Gastroenterol. 1978;13(3):283-8. doi: 10.3109/00365527809179821.
Esophageal acid clearing in normal subjects was studied in different body positions, with an assessment of reproducibility, after dry and water swallows, after smoking, and after alcohol intake. A significant increase in the number of swallows to raise the distal esophageal pH to 5.0 was found in the head-down position (p less than 0.003), after smoking (p less than 0.003), and after alcohol intake (p less than 0.001). It is proposed that the outcome of the acid-clearing test reflects both the transporting capacity of the esophageal muscles and the production of saliva. The precision of the acid-clearing test is not satisfactory, which makes it unsuitable for use in individual cases. It seems, however, well fitted for evaluation of esophageal acid clearing in larger samples.
在不同体位下，对正常受试者进行食管酸清除研究，评估其重复性，并观察干吞和饮水吞咽后、吸烟后以及饮酒后的情况。发现头低位（p<0.003）、吸烟后（p<0.003）和饮酒后（p<0.001），将食管远端pH值升至5.0所需的吞咽次数显著增加。有人提出，酸清除试验的结果反映了食管肌肉的运输能力和唾液分泌情况。酸清除试验的精确度不尽人意，不适用于个体病例。然而，它似乎很适合用于评估较大样本中的食管酸清除情况。
