β-氯-L-丙氨酸对大肠杆菌丙氨酸-缬氨酸转氨酶的抑制作用。
beta-Chloro-L-alanine inhibition of the Escherichia coli alanine-valine transaminase.
作者信息
Whalen W A, Wang M D, Berg C M
出版信息
J Bacteriol. 1985 Dec;164(3):1350-2. doi: 10.1128/jb.164.3.1350-1352.1985.
Abstract
beta-Chloro-L-alanine, an amino acid analog which inhibits a number of enzymes, reversibly inhibited the Escherichia coli K-12 alanine-valine transaminase, transaminase C. This inhibition, along with the inhibition of transaminase B, accounted for the isoleucine-plus-valine requirement of E. coli in the presence of beta-chloro-L-alanine.
摘要
β-氯-L-丙氨酸是一种能抑制多种酶的氨基酸类似物，它可逆地抑制大肠杆菌K-12丙氨酸-缬氨酸转氨酶（转氨酶C）。这种抑制作用，连同对转氨酶B的抑制作用，解释了在存在β-氯-L-丙氨酸的情况下大肠杆菌对异亮氨酸加缬氨酸的需求。
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