Suppr超能文献

皮肤水合作用测量:设备与临床评估之间的比较

Skin Hydration Measurement: Comparison Between Devices and Clinical Evaluations.

作者信息

Park Ju Heon, Choi YoungHwan, Jung Yeon Joo, Lee Taemin, Kim Heeyeon, Cho Youngjoo, Lee Jong Hee

机构信息

Department of Medicine, Sungkyunkwan University School of Medicine, Seoul, Korea.

Department of Dermatology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

出版信息

Ann Dermatol. 2024 Oct;36(5):275-281. doi: 10.5021/ad.23.103.

Abstract

BACKGROUND

The need for an objective method for measuring skin hydration levels is becoming increasingly important. Various devices with different measuring principles for assessing skin hydration have been developed and are widely used.

OBJECTIVE

This study aimed to investigate the reproducibility and correlation between clinical evaluation and skin hydration measurement devices that are the most widely used in the field.

METHODS

A prospective comparative clinical trial was conducted on 184 healthy volunteers. Skin hydration levels were measured using the Corneometer (CM820) and hydration probe (HP: DermaLab Combo) at 3 points: the ventral forearm, the dorsal forearm, and the shin. We used the intraclass correlation coefficient (ICC) to evaluate the reproducibility and Pearson's correlation coefficient (PCC) to evaluate the correlation of each measurement. Simple linear regression was used to analyze the Corneometer and HP skin hydration value changes according to changes in xerosis severity scale (XSS) values, which were evaluated by clinicians.

RESULTS

Both the Corneometer and HP showed significant, excellent reproducibility (ICC for Corneometer: 0.954-0.971, ICC for HP: 0.980-0.986) and significant high positive correlations (PCC: 0.708-0.737) regardless of the measurement site. Both devices showed negative regression coefficients in all measurement sites in XSS analysis, but this was not statistically significant.

CONCLUSION

The Corneometer and HP were both accurate and objective skin hydration measuring devices, regardless of the measurement site. Using reliable and objective devices such as the Corneometer or HP can aid in understanding an individual's skin condition and making more informed decisions for skin care.

TRIAL REGISTRATION

Clinical Research Information Service Identifier: KCT0005146.

摘要

背景

采用客观方法测量皮肤水合水平的需求日益重要。现已开发出多种基于不同测量原理的评估皮肤水合的设备,并得到广泛应用。

目的

本研究旨在调查该领域最广泛使用的临床评估与皮肤水合测量设备之间的可重复性及相关性。

方法

对184名健康志愿者进行了一项前瞻性对比临床试验。使用角质层水合测定仪(CM820)和水合探头(HP:DermaLab Combo)在三个部位测量皮肤水合水平:前臂内侧、前臂外侧和胫骨。我们使用组内相关系数(ICC)评估可重复性,使用皮尔逊相关系数(PCC)评估每次测量的相关性。采用简单线性回归分析角质层水合测定仪和HP皮肤水合值随临床医生评估的皮肤干燥严重程度量表(XSS)值变化的情况。

结果

无论测量部位如何,角质层水合测定仪和HP均显示出显著的、极佳的可重复性(角质层水合测定仪的ICC为0.954 - 0.971,HP的ICC为0.980 - 0.986)以及显著的高度正相关(PCC为0.708 - 0.737)。在XSS分析中,两种设备在所有测量部位均显示出负回归系数,但这在统计学上并不显著。

结论

无论测量部位如何,角质层水合测定仪和HP都是准确且客观的皮肤水合测量设备。使用角质层水合测定仪或HP等可靠且客观的设备有助于了解个体的皮肤状况,并为皮肤护理做出更明智的决策。

试验注册

临床研究信息服务标识符:KCT0005146。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4984/11439984/ed2bd6c886ff/ad-36-275-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验