Smith T M, Kolars J C, Savaiano D A, Levitt M D
Am J Clin Nutr. 1985 Dec;42(6):1197-200. doi: 10.1093/ajcn/42.6.1197.
An increased prevalence of osteoporosis has been observed in lactase-deficient subjects. This association has been attributed to an avoidance of calcium-containing dairy products by lactase-deficient subjects and/or an adverse affect of lactose malabsorption on calcium absorption. Because the lactose in yogurt can be digested and absorbed by hypolactasic subjects, we tested the ability of lactase-deficient subjects and controls to absorb calcium from milk and yogurt. Subjects ingested 270 mg of Ca plus 45Ca in 250 g of milk or 147 g of commercial, unflavored yogurt, and blood radioactivity was assessed at intervals over 24 h. Based on the areas under the blood radioactivity curves, lactase-deficient subjects and controls absorbed calcium equally well from yogurt and milk. Lactase-deficient subjects absorbed 45Ca from both sources at least as well as did the controls. While we found no evidence to indicate that calcium in yogurt is better absorbed than calcium in milk, yogurt remains an excellent source of calcium because this fermented product is well tolerated by lactase-deficient subjects.
在乳糖酶缺乏的人群中,骨质疏松症的患病率有所增加。这种关联被归因于乳糖酶缺乏的人群避免食用含钙的乳制品,和/或乳糖吸收不良对钙吸收的不利影响。由于酸奶中的乳糖可以被低乳糖酶人群消化和吸收,我们测试了乳糖酶缺乏的人群和对照组从牛奶和酸奶中吸收钙的能力。受试者摄入250克牛奶或147克市售原味酸奶中的270毫克钙加45钙,并在24小时内定期评估血液放射性。根据血液放射性曲线下的面积,乳糖酶缺乏的人群和对照组从酸奶和牛奶中吸收钙的情况同样良好。乳糖酶缺乏的人群从这两种来源吸收45钙的情况至少与对照组一样好。虽然我们没有发现证据表明酸奶中的钙比牛奶中的钙吸收更好,但酸奶仍然是钙的优质来源,因为这种发酵产品能被乳糖酶缺乏的人群很好地耐受。