b型流感嗜血杆菌对头孢克洛的敏感性及接种量的影响。
Susceptibility of Haemophilus influenzae type b to cefaclor and influence of inoculum size.
作者信息
Levin R M, Azimi P H, Dunphy M G
出版信息
Antimicrob Agents Chemother. 1982 Nov;22(5):923-5. doi: 10.1128/AAC.22.5.923.
Abstract
Cefaclor appeared to be an effective antibiotic against both beta-lactamase-positive and beta-lactamase-negative strains of Haemophilus influenzae type b when tested with 10(5) colony-forming units per ml. With inocula in excess of 10(6) colony-forming units per ml, these organisms were neither inhibited nor killed at concentrations of 400 micrograms/ml. This inoculum effect was also demonstrated in time-kill curve studies.
摘要
当每毫升接种10⁵个菌落形成单位进行测试时，头孢克洛似乎是一种对b型流感嗜血杆菌的β-内酰胺酶阳性和β-内酰胺酶阴性菌株均有效的抗生素。当接种量超过每毫升10⁶个菌落形成单位时，在400微克/毫升的浓度下，这些微生物既未受到抑制也未被杀死。这种接种量效应在时间-杀菌曲线研究中也得到了证实。
相似文献
1
Susceptibility of Haemophilus influenzae type b to cefaclor and influence of inoculum size.b型流感嗜血杆菌对头孢克洛的敏感性及接种量的影响。
Antimicrob Agents Chemother. 1982 Nov;22(5):923-5. doi: 10.1128/AAC.22.5.923.
2
In-vitro activity of cefaclor, cephalexin and ampicillin against 2458 clinical isolates of Haemophilus influenzae.头孢克洛、头孢氨苄和氨苄西林对2458株流感嗜血杆菌临床分离株的体外活性。
J Antimicrob Chemother. 1988 Jan;21(1):27-31. doi: 10.1093/jac/21.1.27.
3
[In vitro activity of cefaclor against Haemophilus influenzae in comparison to various oral chemotherapeutic agents (author's transl)].
Infection. 1979;7 Suppl 6:532-9. doi: 10.1007/BF01659728.
4
[In vitro activity of cefaclor (author's transl)].头孢克洛的体外活性（作者译）
Infection. 1979;7 Suppl 6:518-26. doi: 10.1007/BF01659726.
5
Reliability of cefaclor, cefazolin, cefamandole, and cephalothin disks to predict susceptibility of Enterobacteriaceae, Staphylococcus species, and Haemophilus influenzae.头孢克洛、头孢唑林、头孢孟多和头孢噻吩药敏纸片预测肠杆菌科细菌、葡萄球菌属细菌及流感嗜血杆菌药敏的可靠性。
Am J Clin Pathol. 1985 Nov;84(5):643-8. doi: 10.1093/ajcp/84.5.643.
6
Summary of laboratory studies on the antibacterial activity of cefaclor.头孢克洛抗菌活性的实验室研究总结。
Postgrad Med J. 1979;55 Suppl 4:22-9.
7
Comparative in vitro microbiological activity and stability of cefaclor.
Postgrad Med J. 1979;55 Suppl 4:9-11.
8
In vitro susceptibility of Haemophilus influenzae to sulfamethoxazole-trimethoprim and cefaclor, cephalexin, and cephradine.流感嗜血杆菌对磺胺甲恶唑-甲氧苄啶以及头孢克洛、头孢氨苄和头孢拉定的体外敏感性
Antimicrob Agents Chemother. 1978 May;13(5):861-4. doi: 10.1128/AAC.13.5.861.
9
Comparative kill and growth rates determined with cefdinir and cefaclor and with Streptococcus pneumoniae and beta-lactamase-producing Haemophilus influenzae.用头孢地尼和头孢克洛以及肺炎链球菌和产β-内酰胺酶的流感嗜血杆菌测定的相对杀灭率和生长率。
Antimicrob Agents Chemother. 1992 Jan;36(1):46-9. doi: 10.1128/AAC.36.1.46.
10
Susceptibility of Haemophilus influenzae to amoxicillin/clavulanic acid, erythromycin, cefaclor, and trimethoprim/sulfamethoxazole.流感嗜血杆菌对阿莫西林/克拉维酸、红霉素、头孢克洛和甲氧苄啶/磺胺甲恶唑的敏感性。
Diagn Microbiol Infect Dis. 1986 Jan;4(1):37-41. doi: 10.1016/0732-8893(86)90054-4.
引用本文的文献
1
Inoculum effect of β-lactam antibiotics.β-内酰胺类抗生素的接种效应。
J Antimicrob Chemother. 2019 Oct 1;74(10):2825-2843. doi: 10.1093/jac/dkz226.
2
Effect of inoculum size on Haemophilus influenzae type b susceptibility to new and conventional antibiotics.接种量对b型流感嗜血杆菌对新型和传统抗生素敏感性的影响。
Antimicrob Agents Chemother. 1983 Aug;24(2):287-9. doi: 10.1128/AAC.24.2.287.
3
Bactericidal activities of chloramphenicol and eleven other antibiotics against Salmonella spp.氯霉素及其他十一种抗生素对沙门氏菌属的杀菌活性
Antimicrob Agents Chemother. 1984 Mar;25(3):327-30. doi: 10.1128/AAC.25.3.327.
4
In vitro activity of Ro 15-8074, a new oral cephalosporin, against Neisseria gonorrhoeae.新型口服头孢菌素Ro 15-8074对淋病奈瑟菌的体外活性
Antimicrob Agents Chemother. 1985 Sep;28(3):461-3. doi: 10.1128/AAC.28.3.461.
5
In vitro activity of Ro 15-8074 and Ro 19-5247 in comparison to cefaclor and cefalexin.
Infection. 1987 Mar-Apr;15(2):122-4. doi: 10.1007/BF01650213.
6
Surveillance study of resistance in Haemophilus species in Greece.希腊嗜血杆菌属耐药性的监测研究。
Eur J Clin Microbiol Infect Dis. 1988 Apr;7(2):186-8. doi: 10.1007/BF01963077.
7
Antibiotic resistance in Haemophilus influenzae: mechanisms, clinical importance and consequences for therapy.流感嗜血杆菌中的抗生素耐药性：机制、临床重要性及对治疗的影响
Eur J Pediatr. 1991 Jun;150(8):534-46. doi: 10.1007/BF02072202.
本文引用的文献
1
PYELONEPHRITIS IN INFANCY AND CHILDHOOD.婴幼儿及儿童期肾盂肾炎
Pediatr Clin North Am. 1964 Aug;11:731-58. doi: 10.1016/s0031-3955(16)31592-9.
2
Urinary tract infection in paralytic poliomyelitis.麻痹性脊髓灰质炎中的尿路感染
Medicine (Baltimore). 1958 Dec;37(4):281-97. doi: 10.1097/00005792-195812000-00001.
3
[Possibilities and limits of antibiotic therapy in treatment of respiratory tract diseases].[抗生素治疗呼吸道疾病的可能性与局限性]
Monatsschr Kinderheilkd (1902). 1956 Mar;104(3):106-7.
4
The role of cefamandole in the treatment of Haemophilus influenzae infections in infants and children.头孢孟多在婴幼儿流感嗜血杆菌感染治疗中的作用。
J Pediatr. 1981 Jun;98(6):995-1000. doi: 10.1016/s0022-3476(81)80616-6.
5
Otitis media. Clinical observations, microbiology, and evaluation of therapy.中耳炎。临床观察、微生物学及治疗评估。
Am J Dis Child. 1968 May;115(5):542-51. doi: 10.1001/archpedi.1968.02100010544003.
6
In vitro antimicrobial activity comparison of cefaclor (compound 99638), cephradine, and cephalothin.
J Antibiot (Tokyo). 1977 Sep;30(9):753-5. doi: 10.7164/antibiotics.30.753.
7
Cefaclor: in vitro spectrum of activity and beta-lactamase stability.头孢克洛：体外活性谱及β-内酰胺酶稳定性
Antimicrob Agents Chemother. 1978 Apr;13(4):584-8. doi: 10.1128/AAC.13.4.584.
8
In vitro susceptibility of Haemophilus influenzae to sulfamethoxazole-trimethoprim and cefaclor, cephalexin, and cephradine.流感嗜血杆菌对磺胺甲恶唑-甲氧苄啶以及头孢克洛、头孢氨苄和头孢拉定的体外敏感性
Antimicrob Agents Chemother. 1978 May;13(5):861-4. doi: 10.1128/AAC.13.5.861.
9
Comparison of in vitro activity of cephalexin, cephradine, and cefaclor.头孢氨苄、头孢拉定和头孢克洛的体外活性比较。
Antimicrob Agents Chemother. 1977 Mar;11(3):470-4. doi: 10.1128/AAC.11.3.470.
10
Treatment of acute otitis media of infancy with cefaclor.用头孢克洛治疗婴儿急性中耳炎。
Am J Dis Child. 1978 Oct;132(10):992-6. doi: 10.1001/archpedi.1978.02120350056011.
Zotero 插件