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解析复杂性:一例罕见的系统性硬化症、类风湿关节炎和系统性红斑狼疮重叠综合征病例

Unraveling the Complexity: A Rare Case of Systemic Sclerosis, Rheumatoid Arthritis, and Systemic Lupus Erythematosus Overlap Syndrome.

作者信息

Gopal Sava Nanda, Vakati Deepthi, David Kanimozhi, Palanisamy Saranya, Rajendran Kannan

机构信息

Internal Medicine, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, IND.

出版信息

Cureus. 2024 Sep 1;16(9):e68405. doi: 10.7759/cureus.68405. eCollection 2024 Sep.

DOI:10.7759/cureus.68405
PMID:39360097
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11446494/
Abstract

Overlap syndromes involving systemic sclerosis (SSc), rheumatoid arthritis (RA), and systemic lupus erythematosus (SLE) are rare and present significant diagnostic and therapeutic challenges. This case report details a 54-year-old female who presented with a constellation of clinical and serological features suggestive of both SSc, RA, and SLE. The patient's clinical course, diagnostic findings, and response to treatment are discussed highlighting the need for a multidisciplinary approach in managing such complex cases.

摘要

涉及系统性硬化症(SSc)、类风湿关节炎(RA)和系统性红斑狼疮(SLE)的重叠综合征较为罕见,且带来了重大的诊断和治疗挑战。本病例报告详细介绍了一名54岁女性,她表现出一系列临床和血清学特征,提示同时患有SSc、RA和SLE。讨论了该患者的临床病程、诊断结果及治疗反应,强调了在管理此类复杂病例时采用多学科方法的必要性。

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本文引用的文献

1
Pathogenesis of autoimmune disease.自身免疫性疾病的发病机制。
Nat Rev Nephrol. 2023 Aug;19(8):509-524. doi: 10.1038/s41581-023-00720-1. Epub 2023 May 10.
2
Systemic sclerosis.系统性硬化症。
Lancet. 2023 Jan 28;401(10373):304-318. doi: 10.1016/S0140-6736(22)01692-0. Epub 2022 Nov 25.
3
Systemic Scleroderma-Definition, Clinical Picture and Laboratory Diagnostics.系统性硬化症——定义、临床表现及实验室诊断
J Clin Med. 2022 Apr 20;11(9):2299. doi: 10.3390/jcm11092299.
4
Clinical Features of Systemic Sclerosis-Mixed Connective Tissue Disease and Systemic Sclerosis Overlap Syndromes.系统性硬化症-混合性结缔组织病和系统性硬化症重叠综合征的临床特征。
Arthritis Care Res (Hoboken). 2021 May;73(5):732-741. doi: 10.1002/acr.24167. Epub 2021 Apr 3.
5
Overlap Syndrome-Systemic Sclerosis, Systemic Lupus Erythematosus and Dermatomyositis - Case Report.重叠综合征——系统性硬化症、系统性红斑狼疮和皮肌炎——病例报告
Curr Health Sci J. 2015 Jul-Sep;41(3):269-273. doi: 10.12865/CHSJ.41.03.13. Epub 2015 Mar 15.
6
Very Early Systemic Sclerosis and Pre-systemic Sclerosis: Definition, Recognition, Clinical Relevance and Future Directions.极早期系统性硬化症和前系统性硬化症:定义、识别、临床相关性及未来方向
Curr Rheumatol Rep. 2017 Sep 18;19(10):65. doi: 10.1007/s11926-017-0684-2.
7
Disease progression in systemic sclerosis-overlap syndrome is significantly different from limited and diffuse cutaneous systemic sclerosis.系统性硬化症重叠综合征的疾病进展与局限性和弥漫性皮肤型系统性硬化症显著不同。
Ann Rheum Dis. 2015 Apr;74(4):730-7. doi: 10.1136/annrheumdis-2013-204487. Epub 2014 Jan 3.
8
Clinical and serological hallmarks of systemic sclerosis overlap syndromes.系统性硬化症重叠综合征的临床和血清学特征。
J Rheumatol. 2011 Nov;38(11):2406-9. doi: 10.3899/jrheum.101248. Epub 2011 Aug 15.
9
Anti-agalactosyl IgG antibodies in Thai patients with rheumatoid arthritis, systemic lupus erythematosus, and systemic sclerosis.泰国类风湿关节炎、系统性红斑狼疮和系统性硬化症患者的抗半乳糖 IgG 抗体。
Clin Rheumatol. 2010 Mar;29(3):241-6. doi: 10.1007/s10067-009-1284-y. Epub 2009 Nov 29.
10
Clinical risk assessment of organ manifestations in systemic sclerosis: a report from the EULAR Scleroderma Trials And Research group database.系统性硬化症器官表现的临床风险评估:来自欧洲抗风湿病联盟硬皮病试验与研究组数据库的报告
Ann Rheum Dis. 2007 Jun;66(6):754-63. doi: 10.1136/ard.2006.062901. Epub 2007 Jan 18.