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尼日利亚幼儿使用氯喹进行疟疾化学预防。III. 其对营养的影响。

Malaria chemoprophylaxis with chloroquine in young Nigerian children. III. Its effect on nutrition.

作者信息

Bradley-Moore A M, Greenwood B M, Bradley A K, Kirkwood B R, Gilles H M

出版信息

Ann Trop Med Parasitol. 1985 Dec;79(6):575-84. doi: 10.1080/00034983.1985.11811964.

DOI:10.1080/00034983.1985.11811964
PMID:3938935
Abstract

The nutrition of a group of Nigerian children who received weekly chemoprophylaxis with chloroquine during their first one or two years of life was compared with the nutrition of a group of children exposed frequently to malaria. Fewer episodes of severe malnutrition and fewer deaths from malnutrition occurred among protected than among control children. Protected children tended to be taller and heavier than control children and to have a larger mid-upper arm circumference. Mean serum albumin and pre-albumin levels were higher in protected than in control children. However differences between the two groups were small and only in a few instances were they statistically significant.

摘要

对一组在生命的头一两年每周接受氯喹化学预防的尼日利亚儿童的营养状况,与一组经常接触疟疾的儿童的营养状况进行了比较。与对照儿童相比,接受预防的儿童中严重营养不良的发作次数和营养不良导致的死亡人数更少。接受预防的儿童往往比对照儿童更高、更重,上臂中部周长更大。接受预防的儿童的血清白蛋白和前白蛋白平均水平高于对照儿童。然而,两组之间的差异很小,只有少数情况下具有统计学意义。

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