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番木瓜植物植物化学成分的抗癌活性评估:一项叙述性综述。

Anticancer Activity of Phytochemicals of the Papaya Plant Assessed: A Narrative Review.

作者信息

Patel Shachi, Rana Karankumar, Arya Param, Nelson Janelle, Hernandez Vanesa, Minakova Victoria

机构信息

Saint James School of Medicine, Chicago, IL, USA.

出版信息

J Cancer Prev. 2024 Sep 30;29(3):58-68. doi: 10.15430/JCP.24.020.

DOI:10.15430/JCP.24.020
PMID:39398111
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11467756/
Abstract

Cancer remains to be a pervasive disease as traditional treatments have plateaued in efficacy. Anticancer research continues to grow in an effort to find novel preventive and treatment measures for cancers. The papaya plant produces several biologically active phytochemicals, which exhibit anti-inflammatory, antibacterial, and anti-oxidative properties. This review explores studies examining these phytochemicals derived from the papaya plant as a potential chemopreventive agent and a cancer therapeutic. Further studies must be done to establish the papaya plant and its phytochemicals as an alternative to traditional cancer treatments.

摘要

由于传统治疗方法的疗效已趋于平稳,癌症仍然是一种普遍存在的疾病。抗癌研究持续发展,旨在寻找针对癌症的新型预防和治疗措施。木瓜植株产生多种具有生物活性的植物化学物质,这些物质具有抗炎、抗菌和抗氧化特性。本综述探讨了关于源自木瓜植株的这些植物化学物质作为潜在化学预防剂和癌症治疗剂的研究。必须开展进一步研究,以确立木瓜植株及其植物化学物质作为传统癌症治疗替代方法的地位。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2788/11467756/b5140716824d/jcp-29-3-58-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2788/11467756/2141e1c4614c/jcp-29-3-58-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2788/11467756/da89158020a2/jcp-29-3-58-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2788/11467756/b5140716824d/jcp-29-3-58-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2788/11467756/2141e1c4614c/jcp-29-3-58-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2788/11467756/da89158020a2/jcp-29-3-58-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2788/11467756/b5140716824d/jcp-29-3-58-f3.jpg

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L. Leaves: Deciphering Its Antioxidant Bioactives, Biological Activities, Innovative Products, and Safety Aspects.L. 叶:解析其抗氧化生物活性、生物活性、创新产品和安全方面。
Oxid Med Cell Longev. 2022 Jun 9;2022:2451733. doi: 10.1155/2022/2451733. eCollection 2022.
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Small RNA sequencing and identification of papaya (Carica papaya L.) miRNAs with potential cross-kingdom human gene targets.
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Mol Genet Genomics. 2022 Jul;297(4):981-997. doi: 10.1007/s00438-022-01904-3. Epub 2022 May 16.
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The antioxidant and anti-inflammatory effects of Carica Papaya Linn. seeds extract on CCl-induced liver injury in male rats.番木瓜籽提取物对 CCl4 诱导的雄性大鼠肝损伤的抗氧化和抗炎作用。
BMC Complement Med Ther. 2021 Dec 30;21(1):302. doi: 10.1186/s12906-021-03479-9.
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Cucurbitacin B controls M2 macrophage polarization to suppresses metastasis via targeting JAK-2/STAT3 signalling pathway in colorectal cancer.葫芦素B通过靶向结直肠癌中的JAK-2/STAT3信号通路控制M2巨噬细胞极化以抑制转移。
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