在印度尼西亚瓦坦索彭从新冠病毒阴性的人类呼吸道标本中鉴定出的呼吸道病毒谱。

Spectrum of respiratory viruses identified from SARS-CoV-2-negative human respiratory tract specimens in Watansoppeng, Indonesia.

作者信息

Idris Irfan, Wahid Isra, Antonjaya Ungke, Johar Edison, Kleib Fiqry Hasan, Sriyani Ida Yus, Dewantari Aghnianditya Kresno, Daming Oderna, Duharing Mustakim, Sappe Fatmawati, Hasan Hajar, Yudhaputri Frilasita Aisyah, Syafruddin Din, Myint Khin Saw Aye

机构信息

Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia.

Oxford University Clinical Research Unit Indonesia, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.

出版信息

Access Microbiol. 2024 Oct 11;6(10). doi: 10.1099/acmi.0.000840.v3. eCollection 2024.

DOI:10.1099/acmi.0.000840.v3

PMID:39399533

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11469065/

Abstract

Respiratory infections account for millions of hospital admissions worldwide. The aetiology of respiratory infections can be attributed to a diverse range of pathogens including viruses, bacteria and fungi. SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2)-negative specimens from Wattansoppeng city, South Sulawesi, were analysed to study the spectrum of respiratory viruses. Samples were screened for influenza virus, enterovirus, Paramyxoviridae, Nipah virus, Coronaviridae and Pneumoviridae. Of 210 specimens, 19 were positive for respiratory syncytial virus (RSV)-A, RSV-B, human parainfluenza virus type 1 (HPIV-1), HPIV-2, human rhinovirus (HRV)-A, HRV-B, HRV-C, human metapneumovirus (HMPV), influenza A virus (IAV) and coxsackievirus A6 (CV-A6). Influenza virus was of seasonal H3N2 subtype. The HMPVs were of genotypes B1 and A2a, while one RSV-A was of the ON-1 genotype. The viruses mostly affected children with unknown severity.

摘要

呼吸道感染导致全球数百万人住院。呼吸道感染的病因可归因于多种病原体，包括病毒、细菌和真菌。对南苏拉威西省瓦坦索彭市的严重急性呼吸综合征冠状病毒2（SARS-CoV-2）阴性样本进行分析，以研究呼吸道病毒谱。对样本进行流感病毒、肠道病毒、副粘病毒科、尼帕病毒、冠状病毒科和肺病毒科筛查。在210份样本中，19份对呼吸道合胞病毒（RSV）-A、RSV-B、1型人副流感病毒（HPIV-1）、HPIV-2、人鼻病毒（HRV）-A、HRV-B、HRV-C、人偏肺病毒（HMPV）、甲型流感病毒（IAV）和柯萨奇病毒A6（CV-A6）呈阳性。流感病毒为季节性H3N2亚型。HMPV为B1和A2a基因型，而一株RSV-A为ON-1基因型。这些病毒主要影响儿童，严重程度未知。