Neijman Marise, Hilgers Frans J M, van den Brekel Michiel W M, van Son Rob J J H, Stuiver Martijn M, van der Molen Lisette
Department of Head and Neck Oncology and Surgery, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Amsterdam Center for Language and Communication (ACLC), University of Amsterdam, Amsterdam, The Netherlands.
Head Neck. 2025 Mar;47(3):801-812. doi: 10.1002/hed.27972. Epub 2024 Oct 23.
This study investigated long-term outcomes of dysphagia rehabilitation with an adjustable resistance training device (Swallowing Exercise Aid, SEA2.0) in laryngectomized individuals.
Seventeen laryngectomized participants who participated in a Clinical Phase II Trial were reevaluated at T3 (approximately 6 months after T2), including an interview, PROMS, oral intake, and swallowing capacity. Results of T3 were compared with the earlier time points T0 (baseline), T1 (after 6 weeks of training), and T2 (after 8 weeks of rest).
All outcomes at T3 remained improved compared to T0. Compared to findings at T2, participants reported some deterioration in swallowing at T3. Swallowing capacity and oral intake slightly decreased. Swallowing-related quality of life slightly improved.
Benefits of swallowing rehabilitation with the SEA2.0 in laryngectomized individuals are still noticeable long term. The need for continued exercising to fully maintain improved function is likely, but the required intensity and extent should be determined in further research.
本研究调查了可调节阻力训练装置（吞咽运动辅助器，SEA2.0）对喉切除患者吞咽功能康复的长期效果。
对参加II期临床试验的17名喉切除参与者在T3（T2后约6个月）进行重新评估，包括访谈、患者报告结局量表（PROMS）、经口摄入量和吞咽能力。将T3的结果与早期时间点T0（基线）、T1（训练6周后）和T2（休息8周后）进行比较。
与T0相比，T3时所有结局均保持改善。与T2时的结果相比，参与者报告T3时吞咽功能有所恶化。吞咽能力和经口摄入量略有下降。吞咽相关生活质量略有改善。
SEA2.0对喉切除患者吞咽功能康复的益处长期仍很明显。可能需要持续锻炼以充分维持改善后的功能，但所需的强度和程度应在进一步研究中确定。
