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含精油的水凝胶：设计与应用的最新进展

Hydrogels with Essential Oils: Recent Advances in Designs and Applications.

作者信息

Chelu Mariana

机构信息

"Ilie Murgulescu" Institute of Physical Chemistry, 202 Spl. Independentei, 060021 Bucharest, Romania.

出版信息

Gels. 2024 Sep 30;10(10):636. doi: 10.3390/gels10100636.

DOI:10.3390/gels10100636
PMID:39451288
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11508064/
Abstract

The innovative fusion of essential oils with hydrogel engineering offers an optimistic perspective for the design and development of next-generation materials incorporating natural bioactive compounds. This review provides a comprehensive overview of the latest advances in the use of hydrogels containing essential oils for biomedical, dental, cosmetic, food, food packaging, and restoration of cultural heritage applications. Polymeric sources, methods of obtaining, cross-linking techniques, and functional properties of hydrogels are discussed. The unique characteristics of polymer hydrogels containing bioactive agents are highlighted. These include biocompatibility, nontoxicity, effective antibacterial activity, control of the sustained and prolonged release of active substances, optimal porosity, and outstanding cytocompatibility. Additionally, the specific characteristics and distinctive properties of essential oils are explored, along with their extraction and encapsulation methods. The advantages and disadvantages of these methods are also discussed. We have considered limitations due to volatility, solubility, environmental factors, and stability. The importance of loading essential oils in hydrogels, their stability, and biological activity is analyzed. This review highlights through an in-depth analysis, the recent innovations, challenges, and future prospects of hydrogels encapsulated with essential oils and their potential for multiple applications including biomedicine, dentistry, cosmetics, food, food packaging, and cultural heritage conservation.

摘要

精油与水凝胶工程的创新性融合为包含天然生物活性化合物的下一代材料的设计与开发提供了乐观的前景。本综述全面概述了含精油水凝胶在生物医学、牙科、化妆品、食品、食品包装以及文化遗产修复应用方面的最新进展。讨论了水凝胶的聚合物来源、制备方法、交联技术和功能特性。突出了含生物活性剂的聚合物水凝胶的独特特性。这些特性包括生物相容性、无毒性、有效的抗菌活性、活性物质的持续和长效释放控制、最佳孔隙率以及出色的细胞相容性。此外，还探讨了精油的具体特性和独特性质，以及它们的提取和包封方法。也讨论了这些方法的优缺点。我们考虑了由于挥发性、溶解性、环境因素和稳定性导致的局限性。分析了在水凝胶中负载精油的重要性、其稳定性和生物活性。本综述通过深入分析，突出了含精油水凝胶的最新创新、挑战和未来前景，以及它们在生物医学、牙科、化妆品、食品、食品包装和文化遗产保护等多种应用中的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8aa4/11508064/4726a125f07c/gels-10-00636-g013.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8aa4/11508064/5b2c24892eaf/gels-10-00636-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8aa4/11508064/48059e00bf79/gels-10-00636-g009.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8aa4/11508064/4726a125f07c/gels-10-00636-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8aa4/11508064/8ac27a3d5839/gels-10-00636-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8aa4/11508064/bb1d1877f508/gels-10-00636-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8aa4/11508064/96a7817cb86d/gels-10-00636-g003.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8aa4/11508064/75ef3679e5d9/gels-10-00636-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8aa4/11508064/0ce098e9b23b/gels-10-00636-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8aa4/11508064/5b2c24892eaf/gels-10-00636-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8aa4/11508064/48059e00bf79/gels-10-00636-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8aa4/11508064/ebd1c02f876e/gels-10-00636-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8aa4/11508064/3408fe3e137e/gels-10-00636-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8aa4/11508064/c4e15def09be/gels-10-00636-g012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8aa4/11508064/4726a125f07c/gels-10-00636-g013.jpg

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